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The nucleophilic lysine residue is commonly targeted site in protein bioconjugation, typically through amine-reactive N-hydroxysuccinimidyl (NHS) esters. [3] To obtain optimal number of deprotonated lysine residues, the pH of the aqueous solution must be below the pKa of the lysine ammonium group, which is around 10.5, so the typical pH of the reaction is about 8 and 9.
A verb that does not follow all of the standard conjugation patterns of the language is said to be an irregular verb. The system of all conjugated variants of a particular verb or class of verbs is called a verb paradigm; this may be presented in the form of a conjugation table.
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.It is intended as introductory material for novices; for more specific and technical definitions from sub-disciplines and related fields, see Glossary of cell biology, Glossary of genetics, Glossary of evolutionary biology, Glossary of ecology ...
A conjugated protein is a protein that functions in interaction with other (non-polypeptide) chemical groups attached by covalent bonding or weak interactions. [ 1 ] Many proteins contain only amino acids and no other chemical groups, and they are called simple proteins.
These conjugated bile acids are often referred to as bile salts. [1] [2] The pKa of the unconjugated bile acids are between 5 and 6.5, and the pH of the duodenum ranges between 3 and 5, so when unconjugated bile acids are in the duodenum, they are almost always protonated (HA form), which makes them relatively insoluble in water. Conjugating ...
Conjugated dienes have conjugated double bonds separated by one single bond. Conjugated dienes are more stable than other dienes because of resonance. Unconjugated dienes have the double bonds separated by two or more single bonds. They are usually less stable than isomeric conjugated dienes. This can also be known as an isolated diene.
Inflection of the Scottish Gaelic lexeme for 'dog', which is cù for singular, chù for dual with the number dà ('two'), and coin for plural. In linguistic morphology, inflection (less commonly, inflexion) is a process of word formation [1] in which a word is modified to express different grammatical categories such as tense, case, voice, aspect, person, number, gender, mood, animacy, and ...
In linguistics and grammar, conjugation has two basic meanings. [1] One meaning is the creation of derived forms of a verb from basic forms, or principal parts.. The second meaning of the word conjugation is a group of verbs which all have the same pattern of inflections.