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Pneumocystis pneumonia (PCP), also known as Pneumocystis jirovecii pneumonia (PJP), is a form of pneumonia that is caused by the yeast-like fungus Pneumocystis jirovecii. [ 3 ] [ 4 ] Pneumocystis specimens are commonly found in the lungs of healthy people although it is usually not a cause for disease. [ 5 ]
X-ray and CT of ground glass opacities and pneumothorax in pneumocystis pneumonia. Diagnosis of Pneumocystis pneumonia is by identifying the organism from a sample of sputum, fluid from affected lungs or a biopsy. [4] [3] A chest X-ray of affected lungs show widespread shadowing in both lungs, with a "bat-wing" pattern and ground glass appearance.
Pneumocystis jirovecii (previously P. carinii) is a yeast-like fungus of the genus Pneumocystis. The causative organism of Pneumocystis pneumonia , it is an important human pathogen , particularly among immunocompromised hosts .
It can be used to identify the yeast-like fungus Pneumocystis jiroveci, [1] which causes a form of pneumonia called Pneumocystis pneumonia (PCP) or pneumocystosis. The cell walls of these organisms are outlined by the brown to black stain. The principle of GMS is the reduction of silver ions, which renders the fungal cell wall black.
Atovaquone, sold under the brand name Mepron, is an antimicrobial medication for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP). [2] Atovaquone is a chemical compound that belongs to the class of naphthoquinones. Atovaquone is a hydroxy-1,4-naphthoquinone, an analog of both ubiquinone and lawsone.
A human pathogen is a pathogen (microbe or microorganism such as a virus, bacterium, prion, or fungus) that causes disease in humans.. The human physiological defense against common pathogens (such as Pneumocystis) is mainly the responsibility of the immune system with help by some of the body's normal microbiota.
Pneumocystis pneumonia (PCP) (originally known as Pneumocystis carinii pneumonia) is relatively rare in healthy, immunocompetent people, but common among HIV-infected individuals. [15] It is caused by Pneumocystis jirovecii.
It includes the single order Pneumocystidales, which contains the single monotypic family Pneumocystidaceae, which in turn contains the genus Pneumocystis, causative agent of Pneumocystis pneumonia. References