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The fornix (from Latin: fornix, lit. 'arch'; pl.: fornices) is a C-shaped bundle of nerve fibers in the brain that acts as the major output tract of the hippocampus. The fornix also carries some afferent fibers to the hippocampus from structures in the diencephalon and basal forebrain. The fornix is part of the limbic system. While its exact ...
The fornix is a C-shaped bundle of axons that begins in the hippocampal formation of both hemispheres, referred to as the fimbria, and extend through the crus of fornix, also known as the posterior pillars. The fimbria section of the fornix is directly connected to the alveus, which is a portion of the hippocampal formation that arises from the ...
Fimbria-fornix fibers are the hippocampal and subicular gateway to and from subcortical brain regions. [10] [11] Different parts of this system are given different names: White myelinated fibers that cover the ventricular (deep) parts of hippocampus make alveus. Fibers that cover the temporal parts of hippocampus make a fiber bundle that is ...
Subfornical organ of a mouse. In this photomicrograph, the subfornical organ (arrow) is located on the undersurface of the fornix in the upper part of the third ventricle. The cells in this coronal section of the brain were colored with a bluish dye ("Nissl stain"). The thalamus is at the bottom of the photo. The bar at the lower right ...
They are located on the undersurface of the brain that, as part of the diencephalon, form part of the limbic system. They are located at the ends of the anterior arches of the fornix. [3] They consist of two groups of nuclei, the medial mammillary nuclei and the lateral mammillary nuclei. [4]
The region is conventionally divided into three divisions. CA3a is the part of the cell band that is most distant from the dentate (and closest to CA1). CA3b is the middle part of the band nearest to the fimbria and fornix connection. CA3c is nearest to the dentate, inserting into the hilus.
A major output goes via the fornix to the lateral septal area and to the mammillary body of the hypothalamus (which the fornix interconnects with the hippocampus). [21] The hippocampus receives modulatory input from the serotonin , norepinephrine , and dopamine systems, and from the nucleus reuniens of the thalamus to field CA1.
These compensatory mechanisms, increasing connectivity in other parts of the brain, may explain why elderly individuals still display executive function as a decline of connectivity is seen in regions of the corpus callosum. [7] Older adults compared to younger adults show poorer performance in balance exercises and tests.