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  2. Asplenia - Wikipedia

    en.wikipedia.org/wiki/Asplenia

    Quinine (with or without clindamycin) is usually an effective treatment. [29] Alert warning - People without a working spleen can carry a card, or wear a special bracelet or necklet which says that they do not have a working spleen. This would alert a healthcare professional to take rapid action if they become seriously ill and cannot notify ...

  3. Splenic sequestration crisis - Wikipedia

    en.wikipedia.org/wiki/Splenic_sequestration_crisis

    Splenic sequestration crisis is a life-threatening illness common in pediatric patients with homozygous sickle cell disease and beta thalassemia. Up to 30% of these children may develop splenic sequestration crisis with a mortality rate of up to 15%. This crisis occurs when splenic vaso-occlusion causes a large percentage of total blood volume ...

  4. Splenectomy - Wikipedia

    en.wikipedia.org/wiki/Splenectomy

    Surgically removed spleen of a child with thalassemia. It is about 15 times larger than normal. A splenectomy is the surgical procedure that partially or completely removes the spleen. The spleen is an important organ in regard to immunological function due to its ability to efficiently destroy encapsulated bacteria.

  5. Polysplenia - Wikipedia

    en.wikipedia.org/wiki/Polysplenia

    Polysplenia is a congenital disease manifested by multiple small accessory spleens, [1] rather than a single, full-sized, normal spleen. Polysplenia sometimes occurs alone, but it is often accompanied by other developmental abnormalities. Conditions associated with polysplenia include gastrointestinal abnormalities, such as intestinal ...

  6. Sanfilippo syndrome - Wikipedia

    en.wikipedia.org/wiki/Sanfilippo_syndrome

    Sanfilippo syndrome. Sanfilippo syndrome, also known as mucopolysaccharidosis type III (MPS III), is a rare lifelong genetic disease that mainly affects the brain and spinal cord. It is caused by a problem with how the body breaks down certain large sugar molecules called glycosaminoglycans (also known as GAGs or mucopolysaccharides).

  7. Kawasaki disease - Wikipedia

    en.wikipedia.org/wiki/Kawasaki_disease

    Named after. Tomisaku Kawasaki. Kawasaki disease (also known as mucocutaneous lymph node syndrome) is a syndrome of unknown cause that results in a fever and mainly affects children under 5 years of age. [6] It is a form of vasculitis, where medium-sized blood vessels become inflamed throughout the body. [1]

  8. ICD-10 - Wikipedia

    en.wikipedia.org/wiki/ICD-10

    ICD-10. ICD-10 is the 10th revision of the International Classification of Diseases (ICD), a medical classification list by the World Health Organization (WHO). It contains codes for diseases, signs and symptoms, abnormal findings, complaints, social circumstances, and external causes of injury or diseases. [1]

  9. Isolated congenital asplenia - Wikipedia

    en.wikipedia.org/wiki/Isolated_congenital_asplenia

    The spleen is an organ within the lymphatic system and its primary function is to filter blood. However, the spleen also plays a key role in immune responses as it detects pathogens within the blood and secretes phagocytes to fight potential infection. Without these immune functions, individuals with isolated congenital asplenia are extremely ...