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In order to affect brain (neuronal) activity, sensory stimulation must be within the frequency range of roughly 0.5 to 25 hertz (Hz) [citation needed]. Touch, photic and auditory stimulation are capable of affecting brain wave activity. A large area of skin must be stimulated to affect brainwaves, which leaves both auditory and photic ...
Histamine has two basic centres, namely the aliphatic amino group and whichever nitrogen atom of the imidazole ring does not already have a proton. Under physiological conditions, the aliphatic amino group (having a pK a around 9.4) will be protonated, whereas the second nitrogen of the imidazole ring (pK a ≈ 5.8) will not be protonated. [11]
The manifestations of histamine intolerance are usually systemic, affecting the entire body; still, these symptoms are often sporadic and non-specific. [5] [6] [7] The onset of symptoms is usually shortly (within a few hours) after specific food or drink consumption, and subsequent remission usually happens in 4-8 weeks of dieting, [8] that is excluding food that causes the onset of symptoms.
In the last two decades, significant advances occurred in our understanding of the neural processing of sounds in primates. Initially by recording of neural activity in the auditory cortices of monkeys [18] [19] and later elaborated via histological staining [20] [21] [22] and fMRI scanning studies, [23] 3 auditory fields were identified in the primary auditory cortex, and 9 associative ...
The fundamental function of this part of the ear is to gather sound energy and deliver it to the eardrum. Resonances of the external ear selectively boost sound pressure with frequency in the range 2–5 kHz. [2] The pinna as a result of its asymmetrical structure is able to provide further cues about the elevation from which the sound originated.
[1] [2] Histamine is a neurotransmitter involved in various physiological processes. There are four main types of histamine receptors: H1, H2, H3, and H4. H1 receptors are linked to allergic responses, H2 to gastric acid regulation, H3 to neurotransmitter release modulation, and H4 to immune system function. There are four known histamine ...
The brain utilizes subtle differences in loudness, tone and timing between the two ears to allow us to localize sound sources. [10] Localization can be described in terms of three-dimensional position: the azimuth or horizontal angle, the zenith or vertical angle, and the distance (for static sounds) or velocity (for moving sounds). [ 11 ]
An H 3 receptor antagonist is a type of antihistaminic drug used to block the action of histamine at H 3 receptors.. Unlike the H 1 and H 2 receptors which have primarily peripheral actions, but cause sedation if they are blocked in the brain, H 3 receptors are primarily found in the brain and are inhibitory autoreceptors located on histaminergic nerve terminals, which modulate the release of ...