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Prostate cancer is the most diagnosed cancer in men in over half of the world's countries, and the leading cause of cancer death in men in around a quarter of countries. [91] Prostate cancer is rare in those under 40 years old, [92] and most cases occur in those over 60 years, [2] with the average person diagnosed at 67. [93]
There are several reasons why PIN is the most likely prostate cancer precursor. [3] PIN is more common in men with prostate cancer. High grade PIN can be found in 85 to 100% of radical prostatectomy specimens, [4] nearby or even in connection with prostate cancer. It tends to occur in the peripheral zone of the prostate.
A histopathologic diagnosis of prostate cancer is the discernment of whether there is a cancer in the prostate, as well as specifying any subdiagnosis of prostate cancer if possible. The histopathologic subdiagnosis of prostate cancer has implications for the possibility and methodology of any subsequent Gleason scoring . [ 1 ]
A young patient with an “aggressive-looking” prostate cancer, whose father had the condition and who carries a BRCA2 mutation, is an entirely different patient from “an 80-year-old man who ...
Prostate cancer is a form of cancer that is typically slow-growing and originates in or on the prostate, a male reproductive gland that surrounds the urethra in proximity of the bladder and rectum. This is a result of malignant cells forming and multiplying at the prostate, which can then spread or metastasize to other organs in the body. [ 1 ]
The crux cordis or crux of the heart (from Latin "crux" meaning "cross") is the area on the lower back side of the heart where the coronary sulcus (the groove separating the atria from the ventricles) and the posterior interventricular sulcus (the groove separating the left from the right ventricle) meet. [1]
The V/Q ratio in the apex is roughly 3.3 and 0.63 in the base, which indicates that perfusion is greater than ventilation towards the base, and the ventilation rate is greater than perfusion towards the apex. [3] Towards the base of the lungs, the fluid volume in the pleural cavity increases due to gravity, resulting in greater intrapleural ...
Prostate cancer staging is the process by which physicians categorize the risk of cancer having spread beyond the prostate, or equivalently, the probability of being cured with local therapies such as surgery or radiation. Once patients are placed in prognostic categories, this information can contribute to the selection of an optimal approach ...
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