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Ribociclib, sold under the brand name Kisqali, is a medication used for the treatment of certain kinds of breast cancer. [4] Ribociclib is a kinase inhibitor. [ 4 ] It was developed by Novartis and Astex Pharmaceuticals .
In a phase 3 clinical trial from the drugmaker Novartis, Kisqali reduced the risk of a patient’s breast cancer coming back by 25% after three years when given in addition to standard treatments ...
Another remaining question surrounding CDK inhibitors as a therapy is if certain cancers will evade or be resistant to treatment. One study showed that 20% of the patients being treated for metastatic ER+ HER2-breast cancer did not respond at all to treatment with a CDK4/6 inhibitor due to preexisting mutations allowing the cancer cells to continue proliferating despite treatment with the drug ...
This list of Latin and Greek words commonly used in systematic names is intended to help those unfamiliar with classical languages to understand and remember the scientific names of organisms. The binomial nomenclature used for animals and plants is largely derived from Latin and Greek words, as are some of the names used for higher taxa , such ...
Astex Pharmaceuticals is a biotechnology company focused on the discovery and development of drugs in oncology and diseases of the central nervous system.Astex was founded in 1999 by Sir Tom Blundell, [1] [2] Chris Abell & Harren Jhoti, [3] and is located in Cambridge, England.
Combination therapy or polytherapy is therapy that uses more than one medication or modality. Typically, the term refers to using multiple therapies to treat a single disease, and often all the therapies are pharmaceutical (although it can also involve non-medical therapy, such as the combination of medications and talk therapy to treat depression).
The name "international scientific vocabulary" was first used by Philip Gove in Webster's Third New International Dictionary (1961). [1] As noted by David Crystal, [2] science is an especially productive field for new coinages.
Science is a systematic discipline that builds and organises knowledge in the form of testable hypotheses and predictions about the universe. [1] [2] Modern science is typically divided into two or three major branches: [3] the natural sciences (e.g., physics, chemistry, and biology), which study the physical world; and the behavioural sciences (e.g., economics, psychology, and sociology ...