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Dimercaprol has long been the mainstay of chelation therapy for lead or arsenic poisoning, [7] and it is an essential drug. [6] It is also used as an antidote to the chemical weapon Lewisite . Nonetheless, because it can have serious adverse effects , researchers have also pursued development of less toxic analogues, [ 7 ] such as succimer .
The compound was reported in about 1994 after a search for chelating agents selective for mercury. It was licensed in 2006 to CTI Science with the long-term goal of using BDTH 2 to treat mercury poisoning. [4] This compound is prepared by treating isophthaloyl dichloride with two equiv of cysteamine: [1] [2]
The lixiviant solution conditions vary in terms of pH, oxidation-reduction potential, presence of chelating agents and temperature, to optimize the rate, extent and selectivity of dissolution of the desired metal component into the aqueous phase. By using chelating agents, one can selectively extract certain metals.
It is used as a chelating agent: In Wilson's disease, a rare genetic disorder of copper metabolism, penicillamine treatment relies on its binding to accumulated copper and elimination through urine. [4] Penicillamine was the second line treatment for arsenic poisoning, after dimercaprol (BAL). [5] It is no longer recommended. [6]
Copper(II) cyanurate (C 3 H Cu N 3 O 3) is an organic compound. It has very few uses, and is more often encountered accidentally, rather than actually synthesised. It has very few uses, and is more often encountered accidentally, rather than actually synthesised.
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A low by-product synthesis route for trisodium N-(1-carboxylatoethyl)iminodiacetate has recently been described, in which alanine is ethoxylated with ethylene oxide in an autoclave to form bis-hydroxyethylaminoalanine and then oxidized to α-ADA at 190 °C with Raney copper under pressure. [6] The yields are over 90% d.Th., the NTA contents ...
We tested 10 of the best Dutch ovens, including options from Le Creuset, Staub, Lodge, and more. These are our top recommendations for your kitchen.
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