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For example GDF6 gene plays an important role in bone development and joint formation. [12] The mutation in these genes can result in Klippel-Feil syndrome. As a result of having congenital Klippel-Feil syndrome, the spinal anatomy of the individual will present abnormal fusion of any two of the seven cervical bones in the neck. [13]
Bertolotti's syndrome is characterized by sacralization of the lowest lumbar vertebral body and lumbarization of the uppermost sacral segment. It involves a total or partial unilateral or bilateral fusion of the transverse process of the lowest lumbar vertebra to the sacrum, leading to the formation of a transitional 5th lumbar vertebra.
The pars interarticularis, or pars for short, is the part of a vertebra located between the inferior and superior articular processes of the facet joint. [1] [2] In the transverse plane, it lies between the lamina and pedicle. In other words, in the axial view, it is the bony mass between the facets that is anterior to the lamina and posterior ...
As with any arthritis, the joint can become enlarged due to the degenerative process. Even small changes to the facet joint can narrow the intervertebral foramen, possibly impinging on the spinal nerve roots within. [3] More advanced cases can involve severe inflammatory responses in the Z-joint, not unlike a swollen arthritic knee.
Facet joints also prevent each vertebra from slipping over the one below. A small capsule surrounds each facet joint providing a nourishing lubricant for the joint. Also, each joint has a rich supply of tiny nerve fibers that provide a painful stimulus when the joint is injured or irritated. Inflamed facets can cause a powerful muscle spasm.
They allow for flexion and extension and limit lateral flexion in the cervical spine. Pathological processes that can occur in these joints include degenerative changes or hypertrophic arthritis, resulting in foraminal stenosis and nerve compression. Foraminal stenosis at this joint is the most common cause of cervical nerve root pressure.
The median atlanto-axial joint is sometimes considered a triple joint: [3] one between the posterior surface of the anterior arch of atlas and the front of the odontoid process; one between the anterior surface of the ligament and the back of the odontoid process; The lateral atlantoaxial joint involves the lateral mass of atlas and axis. [4]
When the structures outside the joint are affected, the term "false ankylosis" has been used in contradistinction to "true ankylosis", in which the disease is within the joint. When inflammation has caused the joint-ends of the bones to be fused together, the ankylosis is termed osseous or complete and is an instance of synostosis. Excision of ...
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