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The 79th United States Congress passed the Federal Food, Drug, and Cosmetic Act Penicillin Amendment on July 6, 1945. [2] The United States public law required the U.S. Food and Drug Administration to certify and test penicillin samplings validating the effectiveness, potency, purification, and safety of the antibiotic drugs.
Penicillin entered mass production in 1944 and revolutionized the treatment of several venereal diseases. Antibiotics are used to treat gonorrhea infections. As of 2016, both ceftriaxone by injection and azithromycin by mouth are most effective.
A sexually transmitted infection (STI), also referred to as a sexually transmitted disease (STD) and the older term venereal disease (VD), is an infection that is spread by sexual activity, especially vaginal intercourse, anal sex, oral sex, or sometimes manual sex.
Penicillin is the most commonly used antibiotic to treat syphilis. Other options may be used if you are allergic to penicillin, or your doctor may recommend a regimen that will allow your body to ...
Between 1945 and 1955 penicillin was used to treat over two million Americans for syphilis, and contact tracing was introduced. Syphilis prevalence dropped to an all-time low by 1955. A total of 6993 cases of primary and secondary syphilis were recorded in 1998, the lowest number since 1941. [ 86 ]
Syphilis can be effectively treated with antibiotics. [4] The preferred antibiotic for most cases is benzathine benzylpenicillin injected into a muscle. [4] In those who have a severe penicillin allergy, doxycycline or tetracycline may be used. [4] In those with neurosyphilis, intravenous benzylpenicillin or ceftriaxone is recommended. [4]
Penicillin by injection; Procaine benzylpenicillin, benzylpenicillin, benzathine penicillin G [3] Edvard Munch 's Inheritance (1897–99) depicts a baby with congenital syphilis and its mother. Congenital syphilis is syphilis that occurs when a mother with untreated syphilis passes the infection to her baby during pregnancy or at birth . [ 4 ]
Many of the syphilis treatment therapies only lead to bacteriostatic results, unless larger concentrations of penicillin are used for bactericidal effects. [ 64 ] [ 65 ] Penicillin overall is the most recommended antibiotic by the Centers for Disease Control, as it shows the best results with prolonged use.
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