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The purpose of HLA Time Management, described in chapter 8 of the HLA Interface Specification, [5] is to guarantee causality and a correct and consistent exchange of time stamped messages (updates and interactions) in Time Stamp Order (TSO), no matter if the federation executes in real-time, faster-than-real-time, slower-than-real-time or as ...
The most prominent aspect of the β-chain is the presence of a large intron, ranging from six to seven kilobases in size. [4] It is present in the first locus (coding for C4A) for all C4 genes and in the second locus (coding for C4B) only in a few C4 genes. [4] The α-chain consists of residues 661-1428, encoding exons 16-33. [4]
The HLA CTL is an interpreted language that is available in an HLA program source file. An interpreter executes HLA CTL statements during the compiling of an HLA source file; hence the name compile-time language. The HLA CTL includes many control statements such as #IF, #WHILE, #FOR, #PRINT, an assignment statement and so on. One can also ...
[4] HLA-DM is a molecular chaperone [5] that works in lysosomes and endosomes in cells of the immune system. It works in APCs like macrophages, dendritic cells, and B cells [6] by interacting with MHC class II molecules. [7] HLA-DM protects the MHC class II molecules from breaking down, and regulates which proteins or peptides bind to them as ...
HLA region of Chromosome 6. The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation of the immune system. [1] The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals. [2]
HLA-C is a locus on chromosome 6, which encodes for many HLA-C alleles that are Class-I MHC receptors. HLA-C, localized proximal to the HLA-B locus, is located on the distal end of the HLA region. Most HLA-C:B haplotypes are in strong linkage disequilibrium and many are as ancient as the human species itself.
HLA class II histocompatibility antigen, DR alpha chain is a protein that in humans is encoded by the HLA-DRA gene. [4] HLA-DRA encodes the alpha subunit of HLA-DR. Unlike the alpha chains of other Human MHC class II molecules, the alpha subunit is practically invariable.
Within molecular and cell biology, HLA-DQ3 (DQ3) is a broad serotype category with split antigens HLA-DQ7, DQ8, and DQ9. Historically, originally recognized as MB3 [ 1 ] a DC4 serotype, DQw3 was one of three early determined antigens recognized as HLA-DQ along with HLA-DQ1 and HLA-DQ2 . [ 2 ]
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