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Omarigliptin (MK-3102) is a potent, long-acting oral antidiabetic drug of the DPP-4 inhibitor class used for once-weekly treatment of type 2 diabetes and currently under development by Merck & Co. [1] It inhibits DPP-4 to increase incretin levels (GLP-1 and GIP), [2] [3] [4] which inhibit glucagon release, which in turn increases insulin secretion, decreases gastric emptying and decreases ...
Merck & Co. traces its origins to its former German parent company Merck Group, which was established by the Merck family in 1668 when Friedrich Jacob Merck purchased a drug store in Darmstadt. [ 27 ] [ 28 ] In 1827, Merck Group evolved from a pharmacy to a drug manufacturer company with the commercial manufacture of morphine . [ 29 ]
Merck was testing vibostolimab along with Keytruda, its top-selling cancer drug, in a late-stage study in patients with resected high-risk melanoma. ... This is the latest setback for the ...
[15] [16] It was then acquired by the Miami-based company Ridgeback Biotherapeutics, which later partnered with Merck & Co. to develop the drug further. [17] Based on positive results in placebo-controlled double-blind randomized clinical trials, [18] [19] molnupiravir was approved for medical use in the United Kingdom in November 2021.
Doravirine, sold under the brand name Pifeltro, is a non-nucleoside reverse transcriptase inhibitor medication developed by Merck & Co. for use in the treatment of HIV/AIDS. Doravirine was approved for medical use in the United States in August 2018.
The approval marks the first indication for Keytruda in MPM in the U.S. Also Read: Merck/Daiichi Sankyo Partnered Lung Cancer Candidate Meets Primary Goal In Late-Stage Study. MPM is a rare ...
Merck's vaccine, branded Capvaxive, helped produce an immune response against all 21 serotypes, or variations of the bacteria, that the shot targeted in a variety of adult populations across studies.
The patent protects Merck's formulation for the drug and its other associated salt forms, hydrates, solvates, prodrugs and isomers. [19] U.S. Patent No. 7973040 was published in 2011. The patent protects the invention by Merck of the macrocyclic compound within the formula as an inhibitor for NS3 protease.
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