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Rheumatology, Immunology. Relapsing polychondritis is a systemic disease characterized by repeated episodes of inflammation and in some cases deterioration of cartilage. The disease can be life-threatening if the respiratory tract, heart valves, or blood vessels are affected. The exact mechanism is poorly understood.
Specialty. Immunology, rheumatology. Polyarteritis nodosa (PAN) is a systemic necrotizing inflammation of blood vessels (vasculitis) affecting medium-sized muscular arteries, typically involving the arteries of the kidneys and other internal organs but generally sparing the lungs' circulation. [3] Small aneurysms are strung like the beads of a ...
Granulomatosis with polyangiitis (GPA), previously known as Wegener's granulomatosis (WG), [1][2][3][4][5] after the German physician Friedrich Wegener, is a rare long-term systemic disorder that involves the formation of granulomas and inflammation of blood vessels (vasculitis). It is an autoimmune disease and a form of vasculitis that affects ...
Myositis, giant cell arteritis. Medication. Corticosteroids. Polymyalgia rheumatica (PMR) is a syndrome experienced as pain or stiffness, usually in the neck, shoulders, upper arms, and hips, but which may occur all over the body. The pain can be sudden or can occur gradually over a period. Most people with PMR wake up in the morning with pain ...
Rheumatology. Remitting seronegative symmetrical synovitis with pitting edema (or sometimes RS3PE) is a rare syndrome identified by symmetric polyarthritis, synovitis, acute pitting edema (swelling) of the back of the hands and/or feet, and a negative serum rheumatoid factor. [2] If no underlying disorder can be identified (idiopathic RS3PE ...
Sjögren's syndrome may be associated with other autoimmune diseases, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) or systemic sclerosis. The inflammation that results progressively damages the glands. [7] Diagnosis is by biopsy of moisture-producing glands and blood tests for specific antibodies. [2]
In antisynthetase syndrome, arthritis is commonly described as a symmetrical, non-erosive polyarthritis of the small hands and feet that can sometimes mimic CTD-associated, rheumatoid, and seronegative inflammatory arthritis. [21] Arthritis is non-specific and occurs in about 18–55% of Idiopathic inflammatory myopathies. [21]
Juvenile idiopathic arthritis (JIA), formerly known as juvenile rheumatoid arthritis (JRA), [1] is the most common chronic rheumatic disease of childhood, affecting approximately 3.8 to 400 out of 100,000 children. [3] Juvenile, in this context, refers to disease onset before 16 years of age, while idiopathic refers to a condition with no ...