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  2. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa.

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]

  4. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The second one was apixaban (Eliquis), approved in Europe in 2011 [2] and in the United States in 2012. [3] The third one edoxaban (Lixiana, Savaysa) was approved in Japan in 2011 and in Europe and the US in 2015. [4] Betrixaban (Bevyxxa) was approved in the US in 2017.

  5. Medicare to save $6B in 2026 from the first ever Part D drug ...

    www.aol.com/finance/medicare-save-6b-2026-first...

    The blood thinner Eliquis is a top seller for Bristol Myers Squibb. CMS Medicare Part D data shows the government spent $15 billion in 2022 on the drug out of a total of $46.4 billion spent on ...

  6. Pharma CEOs grilled by senators over sky-high drug prices - AOL

    www.aol.com/news/pharma-ceos-grilled-senators...

    Bristol Myers Squibb charges an annual list price of about $7,100 for Eliquis in the U.S., compared to around $900 in Canada and about $650 in France. J&J’s Stelara is $79,000 in the U.S., but ...

  7. Bristol-Myers Squibb and Pfizer Announce U.S. FDA Approval of ...

    www.aol.com/news/2012-12-28-bristol-myers-squibb...

    Bristol-Myers Squibb and Pfizer will provide additional information on the FDA approval of Eliquis in a separate press release, to be issued next week. About Bristol-Myers Squibb.

  8. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [8]

  9. FDA Clears Anticlotting Drug Eliquis - AOL

    www.aol.com/news/2012-12-28-fda-clears-anti...

    The Food and Drug Administration has granted approval for the next-generation anticlotting medication Eliquis, the regulator announced in a news release. The drug, administered in the form of a ...

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