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Colonization can initially cause H. pylori induced gastritis, ... Stomach cancer can cause nausea, vomiting, diarrhoea, constipation, and unexplained weight loss. [70]
The role of H. pylori in functional dyspepsia is controversial, and treatment for H. pylori may not lead to complete improvement of a patient's dyspepsia. [6] However, a recent systemic review and meta-analysis of 29 studies published in 2022 suggests that successful treatment of H. pylori modestly improves indigestion symptoms. [18]
[3] [4] [5] Its usefulness in people infected by H. pylori is limited. [3] It is used by mouth (for upper GIT ulcers) and rectally (for radiation proctitis). [3] [5] Common side effects include constipation. [3] Serious side effects may include bezoar formation and encephalopathy. [6] Use appears to be safe in pregnancy and breastfeeding. [6]
Gastritis caused by H. pylori infection is termed Helicobacter pylori induced gastritis, and listed as a disease in ICD11. [6] [7] More than 80% of individuals infected with the bacterium are asymptomatic and it has been postulated that it may play an important role in the natural stomach ecology. [17]
Several epidemiological studies have demonstrated a moderate correlation between dyspepsia in the general population and female sex, smoking, non-steroidal anti-inflammatory medication use, and H pylori infection. [13] In one long-term investigation, a high body mass index was an independent predictor of the emergence of functional dyspepsia. [14]
Atrophic gastritis under low power. H&E stain. Autoimmune metaplastic atrophic gastritis (AMAG) is an inherited form of atrophic gastritis characterized by an immune response directed toward parietal cells and intrinsic factor. [6] Achlorhydria induces G cell (gastrin-producing) hyperplasia, which leads to hypergastrinemia.
A new study has suggested that damage to the upper gastrointestinal tract from conditions such as reflux, peptic ulcers, and prolonged use of NSAIDS may increase Parkinson’s risk by 76%.
Helicobacter suis (H. suis) is a species within the Helicobacter genus of Gram-negative bacteria. [1] Helicobacter pylori is by far the best known Helicobacter species, primarily because humans infected with it may develop gastrointestinal tract diseases such as stomach inflammation, stomach ulcers, duodenal ulcers, stomach cancers of the nonlymphoma type, and various subtypes of extranodal ...