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[81] [82] Concerns regarding the long-term effects of benzodiazepines have been raised since 1980. [83] These concerns are still not fully answered. A review in 2006 of the literature on use of benzodiazepine and nonbenzodiazepine hypnotics concluded that more research is needed to evaluate the long-term effects of hypnotic drugs. [84]
Discontinuing benzodiazepines or antidepressants abruptly due to concerns of teratogenic effects of the medications has a high risk of causing serious complications, so is not recommended. For example, abrupt withdrawal of benzodiazepines or antidepressants has a high risk of causing extreme withdrawal symptoms, including suicidal ideation and ...
Benzodiazepine use disorder (BUD), also called misuse or abuse, [1] is the use of benzodiazepines without a prescription and/or for recreational purposes, which poses risks of dependence, withdrawal and other long-term effects. [2] [3] Benzodiazepines are one of the more common
The long-term effects of benzodiazepines are still not fully understood. Long-term benzodiazepine use is associated with attentional and visuospatial functional impairments. Withdrawal from benzodiazepines can lead to improved alertness and decreased forgetfulness in the elderly. Withdrawal led to statistically significant improvements in ...
A number of studies have drawn an association between long-term benzodiazepine use and neuro-degenerative disease, particularly Alzheimer's disease. [150] It has been determined that long-term use of benzodiazepines is associated with increased dementia risk, even after controlling for protopathic bias. [13]
For example, the Mayo Clinic recommends taking a break from sitting every 30 minutes. The good news is that it doesn’t have to be for long. The good news is that it doesn’t have to be for long.
Sulfonylureas, a class of type 2 diabetes medications, are associated with higher risk of impaired awareness of hypoglycemia when used over the long term in a new study.
The involvement of glutamate in benzodiazepine dependence explains long-term potentiation as well as neuro-kindling phenomena. There is some evidence that a prior history of CNS depressant dependence (e.g. alcohol) increases the risk of dependence on benzodiazepines.