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Radiosensitivity is the relative susceptibility of cells, tissues, organs or organisms to the harmful effect of ionizing radiation. Cells types affected Cells ...
This figure illustrates the typical change in the relative radiosensitivity for a biological effect such as cell death when exposed to radiations of low ionizing density (e.g. x-rays). The hyperbolic relationship shown has a maximum OER of 2.70 for 100% oxygen (at 760 mmHg), with a half-range OER value at 4.2 mmHg or 0.55% of oxygen.
Essentially, radiation targeting in this model is random and must hit a specific location on the cell, such as the DNA, to inactivate it. The model that better aligns with Eukaryotic cells and the cell survival curve is the multi-target model.
Radiation sensitivity is the susceptibility of a material to physical or chemical changes induced by radiation. [1] Examples of radiation sensitive materials are silver chloride, photoresists and biomaterials.
A schematic diagram showing a rectangle being irradiated by an external source (in red) of radiation (shown in yellow) A schematic diagram showing a rectangle being irradiated by radioactive contamination (shown in red) which is present on an external surface such as the skin; this emits radiation (shown in yellow), which can enter the animal's ...
Effective dose is a dose quantity in the International Commission on Radiological Protection (ICRP) system of radiological protection. [1]It is the tissue-weighted sum of the equivalent doses in all specified tissues and organs of the human body and represents the stochastic health risk to the whole body, which is the probability of cancer induction and genetic effects, of low levels of ...
The precise treatment intent (curative, adjuvant, neoadjuvant therapeutic, or palliative) will depend on the tumor type, location, and stage, as well as the general health of the patient. Total body irradiation (TBI) is a radiation therapy technique used to prepare the body to receive a bone marrow transplant.
The NRC's definition of dose equivalent is "the product of the absorbed dose in tissue, quality factor, and all other necessary modifying factors at the location of interest." However, it is apparent from their definition of effective dose equivalent that "all other necessary modifying factors" excludes the tissue weighting factor. [ 17 ]