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653361 17969 Ensembl ENSG00000158517 ENSMUSG00000015950 UniProt P14598 Q09014 RefSeq (mRNA) NM_000265 NM_001286037 NM_010876 RefSeq (protein) NP_000256 NP_001272966 NP_035006 Location (UCSC) Chr 7: 74.77 – 74.79 Mb Chr 5: 134.25 – 134.26 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Neutrophil cytosol factor 1, also known as p47phox, is a protein that in humans is encoded by ...
Common examples of neurotoxins include lead, [7] ethanol (drinking alcohol), [8] glutamate, [9] nitric oxide, [10] botulinum toxin (e.g. Botox), [11] tetanus toxin, [12] and tetrodotoxin. [6] Some substances such as nitric oxide and glutamate are in fact essential for proper function of the body and only exert neurotoxic effects at excessive ...
Tetanus toxin (TeNT) is an extremely potent neurotoxin produced by the vegetative cell of Clostridium tetani [1] in anaerobic conditions, causing tetanus. It has no known function for clostridia in the soil environment where they are normally encountered. It is also called spasmogenic toxin, tentoxilysin, tetanospasmin, or tetanus neurotoxin.
The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. [5] It is a 13kbp gene on chromosome 21q22.3 that encodes 545 amino acids. [6] AIRE is a transcription factor expressed in the medulla [broken anchor] (inner part) of the thymus.
α-Bungarotoxin is one of the bungarotoxins, components of the venom of the elapid Taiwanese banded krait snake (Bungarus multicinctus).It is a type of α-neurotoxin, a neurotoxic protein that is known to bind competitively and in a relatively irreversible manner to the nicotinic acetylcholine receptor found at the neuromuscular junction, causing paralysis, respiratory failure, and death in ...
Toxic shock syndrome toxin-1 (TSST-1) is a superantigen with a size of 22 kDa [1] produced by 5 to 25% of Staphylococcus aureus isolates. It causes toxic shock syndrome (TSS) by stimulating the release of large amounts of interleukin-1, interleukin-2 and tumor necrosis factor. In general, the toxin is not produced by bacteria growing in the ...
Eosinophil-derived neurotoxin is an enzyme that in humans is encoded by the RNASE2 gene. [5] [6] [7]The protein encoded by this gene is found in eosinophil granulocytes.It is closely related to the eosinophil cationic protein (RNASE3) from which it diverged ~50 million years ago after the split between the old world and the new world monkeys. [8]
The three-dimensional structure of alpha-bungarotoxin, an alpha-neurotoxin from the venom of Bungarus multicinctus. Gold links indicate disulfide bonds. From 1] α-Neurotoxins are a group of neurotoxic peptides found in the venom of snakes in the families Elapidae and Hydrophiidae. They can cause paralysis, respiratory failure, and death.