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The first avian picornavirus to have its genome sequenced, [3] it causes epidemic tremor in chickens. Tremovirus is of economic importance to chicken farmers because it causes a drop in egg production in laying hens, and neurological diseases in chicks less than three weeks old.
Management of ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) focuses on symptoms management, as no treatments that address the root cause of the illness are available. [1]: 29 Pacing, or regulating one's activities to avoid triggering worse symptoms, is the most common management strategy for post-exertional malaise.
Treatment is usually supportive in nature while also providing antiviral drug therapy. The primary exception to this is herpes simplex encephalitis, which is treatable with acyclovir . Prognosis is good for most individuals who are infected by an encephalitic virus but is poor among those who develop severe symptoms, including viral encephalitis.
Encephalomyelitis is inflammation of the brain and spinal cord. Various types of encephalomyelitis include: Acute disseminated encephalomyelitis or postinfectious encephalomyelitis, a demyelinating disease of the brain and spinal cord, possibly triggered by viral infection. [1] [2] Encephalomyelitis disseminata, a synonym for multiple sclerosis.
It can be further categorized in three subtypes: antibody-negative probable autoimmune encephalitis, autoimmune limbic encephalitis and acute disseminated encephalomyelitis. [4] One therapeutic approach to seronegative autoimmune encephalitis is using as a first-line treatment corticosteroids and intravenous immunoglobulin. [4]
Despite ample evidence that ME/CFS is an organic disease, many clinicians do not recognise it as genuine or underestimate its seriousness. [6] [1] [4] A 2020 literature review found that “a third to a half of all GPs did not accept ME/CFS as a genuine clinical entity and, even when they did, they lacked confidence in diagnosing or managing it.” [4]
Acute disseminated encephalomyelitis: Central nervous system: Unknown Confirmed 0.8 per 100,000 [53] Acute motor axonal neuropathy: Peripheral nerves: Anti-GM1: Confirmed Part of Guillain-Barré syndrome prevalence [54] Anti-NMDA receptor encephalitis: Brain: Anti-NMDA receptor: Confirmed 1.5 per million [55] Autoimmune encephalitis: Brain
[12] [33]: 57 Finally, sleep disorders, coeliac disease, and side effects of medications may also explain symptoms. [12] Joint and muscle pain without swelling or inflammation is a common feature of ME/CFS, but is more closely associated with fibromyalgia. Modern definitions of fibromyalgia not only include widespread pain but also fatigue ...