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Crizanlizumab, sold under the brand name Adakveo among others, is a monoclonal antibody medication that binds to P-selectin. [3] It is a medication used to reduce the frequency of vaso-occlusive crisis in people aged 16 years and older who have sickle cell anemia. [3] [4] [6] It is given by injection into a vein. [3] [4]
47 749.46 g·mol −1 N Y (what is this?) (verify) Certolizumab pegol , sold under the brand name Cimzia , is a biopharmaceutical medication for the treatment of Crohn's disease , [ 4 ] [ 5 ] rheumatoid arthritis , psoriatic arthritis and ankylosing spondylitis .
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As of 2015, while eculizumab used for paroxysmal nocturnal hemoglobinuria was associated with 1.13 additional life years and 2.45 quality of life years QALYs, there has been a high incremental cost (CAN$5.24 million) and a substantial opportunity cost. A 2014 Canadian study calculated the cost per life-year-gained with treatment as CAN$4.62 ...
145 211.51 g·mol −1 Rozanolixizumab , sold under the brand name Rystiggo , is a monoclonal antibody used for the treatment of myasthenia gravis . [ 1 ] Rozanolixizumab is a humanized and chimeric monoclonal antibody; [ 4 ] and is a neonatal Fc receptor blocker.
Clinical trial number NCT05232825 for "A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis (Ocarina II)" at ClinicalTrials.gov
Nevertheless, clinical trials continue for various diseases like multiple myeloma [3] and diabetes mellitus type 1 [4] [5] as of July 2009. Visilizumab has also been radiolabelled with technetium-99m for imaging T cells. [6]
Etrolizumab (rhuMAb Beta7) is a biopharmaceutical drug candidate being developed for the treatment of ulcerative colitis and Crohn's disease.It is a humanized monoclonal antibody against the β7 subunit of integrins α4β7 and αEβ7. [1]
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261