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Mitomycin C is a potent DNA crosslinker.A single crosslink per genome has shown to be effective in killing bacteria. This is accomplished by reductive activation of mitomycin to form a mitosene, which reacts successively via N-alkylation of two DNA bases.
McFarland standards. No. 0.5, 1 and 2. In microbiology, McFarland standards are used as a reference to adjust the turbidity of bacterial suspensions so that the number of bacteria will be within a given range to standardize microbial testing.
In rats, this dose was 1000 mg/kg/day, which is approximately 24 times a human dose of 200 mg twice daily based on mg/m 2 /day. In rabbits, the highest dose tested was 90 mg/kg/day, which is approximately four times a human dose of 200 mg twice daily based on mg/m 2 /day. This dose produced severe maternal toxicity and resulted in fetal ...
The tissue response (y-axis) to an agonist, in log concentration (x-axis), in the presence of different antagonist concentrations. The EC 50 of the agonist is represented by the x co-ordinate that corresponds with the half-maximum of the leftmost curve.
Catalase is a common enzyme found in nearly all living organisms exposed to oxygen (such as bacteria, plants, and animals) which catalyzes the decomposition of hydrogen peroxide to water and oxygen. [5] It is a very important enzyme in protecting the cell from oxidative damage by reactive oxygen species (ROS).
It is found in soil, water, skin flora, and most human-made environments throughout the world. As a facultative anaerobe , P. aeruginosa thrives in diverse habitats. It uses a wide range of organic material for food; in animals, its versatility enables the organism to infect damaged tissues or those with reduced immunity.
Below the CMC point, interfacial tension between oil and water phase is no longer effectively reduced. [10] If the concentration of the surfactant is kept a little above the CMC, the additional amount covers the dissolution with existing brine in the reservoir. It is desired that the surfactant will work at the lowest interfacial tension (IFT).
Biogas is the ultimate waste product of the bacteria feeding off the input biodegradable feedstock [112] (the methanogenesis stage of anaerobic digestion is performed by archaea, a micro-organism on a distinctly different branch of the phylogenetic tree of life to bacteria), and is mostly methane and carbon dioxide, [113] [114] with a small ...