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  2. Cirrhosis - Wikipedia

    en.wikipedia.org/wiki/Cirrhosis

    Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, chronic liver failure or chronic hepatic failure and end-stage liver disease, is an acute condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue and regenerative nodules as a result of chronic liver disease.

  3. Chronic liver disease - Wikipedia

    en.wikipedia.org/wiki/Chronic_liver_disease

    Chronic liver disease in the clinical context is a disease process of the liver that involves a process of progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis. [1] "Chronic liver disease" refers to disease of the liver which lasts over a period of six months.

  4. Hepatomegaly - Wikipedia

    en.wikipedia.org/wiki/Hepatomegaly

    A complete blood test can help distinguish intrinsic liver disease from extrahepatic bile-duct obstruction. [19] An ultrasound of the liver can reliably detect a dilated biliary-duct system, [20] it can also detect the characteristics of a cirrhotic liver. [21] Computerized tomography (CT) can give accurate anatomical information for a complete ...

  5. Liver disease - Wikipedia

    en.wikipedia.org/wiki/Liver_disease

    Liver diseases, including conditions such as non-alcoholic fatty liver disease (NAFLD), alcohol-related liver disease (ALD), and viral hepatitis, are significant public health concerns worldwide. In the United States, NAFLD is the most common chronic liver condition, affecting approximately 24% of the population, with the prevalence rising due ...

  6. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    In patients with liver disease, international normalized ratio (INR) can be used as a marker of liver synthetic function as it includes factor VII, which has the shortest half life (2–6 hours) of all coagulation factors measured in INR. An elevated INR in patients with liver disease, however, does not necessarily mean the patient has a ...

  7. Parenchyma - Wikipedia

    en.wikipedia.org/wiki/Parenchyma

    The liver parenchyma is the functional tissue of the organ made up of around 80% of the liver volume as hepatocytes. The other main type of liver cells are non-parenchymal. Non-parenchymal cells constitute 40% of the total number of liver cells but only 6.5% of its volume. [11]

  8. Metabolic dysfunction–associated steatotic liver disease

    en.wikipedia.org/wiki/Metabolic_dysfunction...

    Metabolic dysfunction–associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), [a] is a type of chronic liver disease. This condition is diagnosed when there is excessive fat build-up in the liver ( hepatic steatosis ), and at least one metabolic risk factor.

  9. Acute liver failure - Wikipedia

    en.wikipedia.org/wiki/Acute_liver_failure

    Acute liver failure is defined as "the rapid development of hepatocellular dysfunction, specifically coagulopathy and mental status changes (encephalopathy) in a patient without known prior liver disease". [23] page 1557