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Bezafibrate (marketed as Bezalip and various other brand names) is a fibrate drug used as a lipid-lowering agent to treat hyperlipidaemia. It helps to lower LDL cholesterol and triglyceride in the blood , and increase HDL .
Prostaglandins are lipids throughout the entire body that have a hormone-like function. [2] In pregnancy, PGF 2α is medically used to sustain contracture and provoke myometrial ischemia to accelerate labor and prevent significant blood loss in labor. [3] Additionally, PGF 2α has been linked to being naturally involved in the process of labor.
Hypercoagulability in pregnancy likely evolved to protect women from hemorrhage at the time of miscarriage or childbirth. In developing countries, the leading cause of maternal death is still hemorrhage. [25] In the United States 2011-2013, hemorrhage made up of 11.4% and pulmonary embolisms made up of 9.2% of all pregnancy-related deaths. [26]
Fetal hemoglobin, or foetal haemoglobin (also hemoglobin F, HbF, or α 2 γ 2) is the main oxygen carrier protein in the human fetus. Hemoglobin F is found in fetal red blood cells , and is involved in transporting oxygen from the mother's bloodstream to organs and tissues in the fetus.
A well known agonist are fibrates and in the clinical trials, there was a significant biochemical response in most patients. [129] A combination therapy with bezafibrate showed remarkable biochemical improvement, with 67% of patients normalizing their alkaline phosphatase levels. [130]
Prostaglandin E 2 (PGE 2), also known as dinoprostone, is a naturally occurring prostaglandin with oxytocic properties that is used as a medication. [2] [3] [4] Dinoprostone is used in labor induction, bleeding after delivery, termination of pregnancy, and in newborn babies to keep the ductus arteriosus open.
When fetal kidneys begin to function around week 16, fetal urine also contributes to the fluid. [1] In earlier times, it was believed that the amniotic fluid was composed entirely of excreted fetal urine. The fluid is absorbed through the fetal tissue and skin. [2] After 22 to 25 week of pregnancy, keratinization of an embryo's
In men with azoospermia, a positive test for inhibin B slightly raises the chances for successfully achieving pregnancy through testicular sperm extraction (TESE), although the association is not very substantial, having a sensitivity of 0.65 (95% confidence interval [CI]: 0.56–0.74) and a specificity of 0.83 (CI: 0.64–0.93) for prediction ...