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  2. 1775–1782 North American smallpox epidemic - Wikipedia

    en.wikipedia.org/wiki/1775–1782_North_American...

    The most common type of smallpox, ordinary, historically has devastated populations with a 30% death rate. The smallpox virus is transmittable through bodily fluids and materials contaminated with infected materials. Generally, face-to-face contact is required for an individual to contract smallpox as a result of an interaction with another human.

  3. History of smallpox - Wikipedia

    en.wikipedia.org/wiki/History_of_smallpox

    A British sailor disembarking HMS Seahorse brought smallpox to Boston. 5759 people were infected and 844 died. 1736: Pennsylvania: 1738: South Carolina: 1770s: West Coast of North America: 1770s Pacific Northwest smallpox epidemic At least 30% (tens of thousands) of the Northwestern Native Americans die from smallpox. [39] [40] 1781–1783 ...

  4. 1721 Boston smallpox outbreak - Wikipedia

    en.wikipedia.org/wiki/1721_Boston_smallpox_outbreak

    Cotton Mather believed inoculation was a divine gift to protect people from smallpox [17] [5] and Boylston felt duty-bound as a physician to protect his children and others from smallpox. [4] Many contemporary Bostonians, however, were terrified of smallpox spreading from inoculated patients [ 18 ] [ 3 ] and outraged at the idea of deliberately ...

  5. 1738–1739 North Carolina smallpox epidemic - Wikipedia

    en.wikipedia.org/wiki/1738–1739_North_Carolina...

    The epidemic was probably spread to the Cherokee by white traders in the summer of 1739. The virus may also have come from Spanish Florida. 900 Cherokees had joined the British to fight the Spanish in Florida in 1739, and may have brought smallpox back with them. Cherokee "religious physicians" blamed the plague on "adulterous intercourse ...

  6. 1770s Pacific Northwest smallpox epidemic - Wikipedia

    en.wikipedia.org/wiki/1770s_Pacific_Northwest...

    The 1520s smallpox epidemic spread from Mesoamerica into adjacent maize-growing regions in North America.A population decline in the Columbia Basin, evidenced archaeologically by a sharp regional decline in artifacts and structures in the early 1500s, has been tentatively linked to a spread of this outbreak, but greatly predates any written record in the region.

  7. Diseases and epidemics of the 19th century - Wikipedia

    en.wikipedia.org/wiki/Diseases_and_epidemics_of...

    Smallpox is caused by either of the two viruses, Variola major and Variola minor. Smallpox vaccine was available in Europe, the United States, and the Spanish Colonies during the last part of the century. [4] [5] The Latin names of this disease are Variola Vera. The words come from various (spotted) or varus (pimple).

  8. Onesimus (Bostonian) - Wikipedia

    en.wikipedia.org/wiki/Onesimus_(Bostonian)

    Onesimus (late 1600s–1700s [1]) was an African (likely Akan) man who was instrumental in the mitigation of smallpox in Boston, Massachusetts.. He introduced his enslaver, Puritan clergyman Cotton Mather, to the principle and procedure of the variolation method of inoculation, which prevented smallpox and laid the foundation for the development of vaccines.

  9. Native American disease and epidemics - Wikipedia

    en.wikipedia.org/wiki/Native_American_disease...

    During the 1770s, smallpox killed at least 30% (tens of thousands) of the Northwestern Native Americans. [74] [75] The smallpox epidemic of 1780–1782 brought devastation and drastic depopulation among the Plains Indians. [76] By 1832, the federal government of the United States established a smallpox vaccination program for Native Americans. [77]