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Ductal carcinoma in situ (DCIS), also known as intraductal carcinoma, is a pre-cancerous or non-invasive cancerous lesion of the breast. [ 1 ] [ 2 ] DCIS is classified as Stage 0. [ 3 ] It rarely produces symptoms or a breast lump that can be felt, typically being detected through screening mammography .
For decades, the diagnosis of DCIS has routinely led to surgery–a mastectomy or a lumpectomy (a partial breast resection) that’s often combined with radiation treatment and possibly, a five ...
After a lumpectomy is performed for DCIS, local radiation therapy is typically performed to help eliminate microscopic-level disease. Axillary sentinel lymph node biopsy, as a method of screening for metastatic disease in otherwise non-invasive DCIS, is falling out of favor because the risks of procedure outweigh any effect on outcomes. [7]
The trial, called Comparing an Operation to Monitoring with or without Endocrine Therapy (COMET), involved nearly 1,000 women diagnosed with low-risk DCIS (about half of U.S. cases are this type).
Breast-conserving surgery may also be used in cases of biopsy-proven invasive breast cancer or biopsy-proven ductal carcinoma in situ. In the assessment of the tumor, the surgeon should assess the ability to resect the tumor with clear margins while providing a cosmetic result that is acceptable to the patient. [3]
A review of 10,485 individuals all of whom had early stage N1 (<2 cm. in size) or N2 (2 to <5 cm. in size) IPC tumors that had not metastasized to lymph nodes or distant tissues reported that lumpectomy plus adjuvant radiation therapy produced significantly better mean survival times (16.8 years) than lumpectomy (14.2 years) or mastectomy (14.9 ...
Greg Doherty/Getty Images Danielle Fishel has officially completed her treatment for breast cancer — but not without some painful side effects. Fishel, 43, shared she was “officially” done ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 29 January 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical Oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...
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