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Hypokalemia is a low level of potassium (K +) in the blood serum. [1] Mild low potassium does not typically cause symptoms. [3] Symptoms may include feeling tired, leg cramps, weakness, and constipation. [1] Low potassium also increases the risk of an abnormal heart rhythm, which is often too slow and can cause cardiac arrest. [1] [3]
[1] Inadequate replacement of potassium losses during diarrhea can lead to potassium depletion and hypokalaemia (low serum potassium) especially in children with malnutrition. This can potentially cause muscle weakness, impaired kidney function, and cardiac arrhythmia.
[3] [14] Stabilization of cardiac muscle cells is done by administering calcium intravenously. [3] Shift of potassium into the cells is done using both insulin and albuterol inhalers. [3] Excretion of potassium from the body is done using either hemodialysis, loop diuretics, or a resin that causes potassium to be excreted in the fecal matter. [3]
Normal potassium levels are between 3.5 and 5.0 mmol/L (3.5 and 5.0 mEq/L) with levels below 3.5 mmol/L defined as hypokalemia. [21] [28] It is classified as severe when levels are less than 2.5 mmol/L. [21] Low levels may also be suspected based on an electrocardiogram (ECG). [21] Hyperkalemia is a high level of potassium in the blood serum. [21]
The trans-tubular potassium gradient (TTKG) is an index reflecting the conservation of potassium in the cortical collecting ducts (CCD) of the kidneys. It is useful in diagnosing the causes of hyperkalemia or hypokalemia. [1] [2] The TTKG estimates the ratio of potassium in the lumen of the CCD to that in the peritubular capillaries.
3) are used to calculate the anion gap. (As discussed above, potassium may or may not be used, depending on the specific lab.) [citation needed] The cations calcium (Ca 2+) and magnesium (Mg 2+) are also commonly measured, but they aren't used to calculate the anion gap.
Mathematically, if the change in the numerator is similar to the change in the denominator, the delta ratio will be close to 1. Since the anions are unable to diffuse out of the bloodstream, while bicarbonate and hydrogen ions diffuse with ease (as H 2 CO 3, carbonic acid), the usual result will be closer to a delta ratio of 1 to 2.
The recommended daily amount of drinking water for humans varies. [1] It depends on activity, age, health, and environment.In the United States, the Adequate Intake for total water, based on median intakes, is 4.0 litres (141 imp fl oz; 135 US fl oz) per day for males older than 18, and 3.0 litres (106 imp fl oz; 101 US fl oz) per day for females over 18; it assumes about 80% from drink and 20 ...
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