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Podophyllotoxin (PPT) is the active ingredient in Podofilox, a medical cream used to treat genital warts and molluscum contagiosum. [2] It is not recommended for HPV infections without external warts. [ 2 ]
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A 0.15–0.5% podophyllotoxin (also called podofilox) solution in a gel or cream. It can be applied by the patient to the affected area and is not washed off. It is the purified and standardized active ingredient of podophyllin (see below). Podofilox is safer and more effective than podophyllin. [29]
Layers of the skin. Drugs administered through topical application can act locally or systemically. [1] [6] However, the drug molecules must first be retained in and penetrate the surface layer of the skin. [6] Absorption of the drug through the skin surface is a passive process of diffusion.
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