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Xenon-133 (sold as a drug under the brand name Xeneisol, ATC code V09EX03 ) is an isotope of xenon. It is a radionuclide that is inhaled to assess pulmonary function, and to image the lungs. [18] It is also used to image blood flow, particularly in the brain. [19] 133 Xe is also an important fission product.
Xenon has been used as a general anesthetic, but it is more expensive than conventional anesthetics. [154] Xenon interacts with many different receptors and ion channels, and like many theoretically multi-modal inhalation anesthetics, these interactions are likely complementary. Xenon is a high-affinity glycine-site NMDA receptor antagonist. [155]
A 2003 publication by the International Atomic Energy Agency confirms the frequent use of most of the tracers above, and says that manganese-56, sodium-24, technetium-99m, silver-110m, argon-41, and xenon-133 are also used extensively because they are easily identified and measured. [13]
By the early 1960s, in southern Scandinavia, Niels A. Lassen, David H. Ingvar, and Erik Skinhøj developed techniques that provided the first blood flow maps of the brain, which initially involved xenon-133 inhalation; [12] an intra-arterial equivalent was developed soon after, enabling measurement of the local distribution of cerebral activity ...
It is produced in medical cyclotrons, usually from oxygen-18, and then chemically attached to a pharmaceutical formulation. ... Xenon-133. 133 Xe is a gamma emitter ...
The radio-pharmaceutical Xenon-133 often is packaged in glass ampoules [3] and specially-shaped glass ampoules have long been used for samples of gaseous elements, such as all of the noble gases save radon (mainly because it is radioactive with a half-life less than half a week) and special thick-walled quartz and fluorite ampoules under high ...
The Food and Drug Administration (FDA) has revoked the use of Red Dye No. 3 (also known as erythrosine, Red Dye 3, FD&C Red No. 3 and Red No. 3) in food and ingested drugs as of January 15, ...
Many radiopharmaceuticals use technetium-99m (Tc-99m) which has many useful properties as a gamma-emitting tracer nuclide. In the book Technetium a total of 31 different radiopharmaceuticals based on Tc-99m are listed for imaging and functional studies of the brain , myocardium , thyroid , lungs , liver , gallbladder , kidneys , skeleton ...