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Although a prospective cohort study of middle-aged women indicated that some flavonoid-rich foods are associated with a reduction in all-cause mortality, frequent grapefruit consumption was associated with a small increase in all-cause mortality, possibly because of the clinically significant drug interactions of the non-flavonoid components. [8]
For example, when the blood pressure drug felodipine is taken with grapefruit juice rather than water, levels of the medication in the blood can more than double and result in headache, irregular ...
It’s these bioactive compounds and antioxidants that are the keys to lentils ability to help reduce blood pressure, LDL cholesterol, and the risk of chronic cardiovascular disease. Just one cup ...
Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]
LDL cholesterol is produced naturally by the body, but eating a diet high in saturated fat, trans fats, and cholesterol can increase LDL levels. [43] Elevated LDL levels are associated with diabetes, hypertension, hypertriglyceridemia, and atherosclerosis. In a fasting lipid panel, a LDL greater than 160 mg/dL is abnormal. [37] [39]
Vitamin C in grapefruit helps promote collagen production, which supports skin health, registered dietitian Samantha Cassetty notes, including grapefruit on her list of the healthiest fruits.
In addition to plaque formation, LDL-C molecules can undergo oxidation. [1] Oxidation can cause further accumulation of cholesterol and the release of inflammatory cytokines, which damages the blood vessels. [1] [7] Due to the damaging effects of LDL-C, high levels increase the risk for cardiovascular disease and indicate dyslipidemia. [1]
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