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The renal medulla (Latin: medulla renis 'marrow of the kidney') is the innermost part of the kidney. The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which then splits up to form the segmental arteries which then branch to form interlobar arteries.
Diagram outlining movement of ions in nephron, with the collecting ducts on the right. The collecting duct system is the final component of the kidney to influence the body's electrolyte and fluid balance. In humans, the system accounts for 4–5% of the kidney's reabsorption of sodium and 5% of the kidney's reabsorption of water. At times of ...
The medulla consists of one or more pyramids, the bases of which start from corticomedullary border. Medulla pyramid with overlying cortex comprises the renal lobe. [28] In multilobar kidneys, the pyramids are separated from each other by dipped into the kidney areas of cortical tissue known as the renal columns. [61]
The simplest type of kidney in mammals is the unipapillary kidney, consisting of a cortex, medulla, and renal pelvis. [163] But the unipapillary kidney is limited by the number of nephrons at which it functions optimally. [20] It is assumed that unipapillary kidney was the original kidney structure in mammals, from which multilobar kidneys ...
The kidney is responsible for about half of the total gluconeogenesis in fasting humans. The regulation of glucose production in the kidney is achieved by action of insulin, catecholamines and other hormones. [14] Renal gluconeogenesis takes place in the renal cortex. The renal medulla is incapable of producing glucose due to absence of ...
Within the nephron of the kidney, the ascending limb of the loop of Henle is a segment of the heterogenous loop of Henle downstream of the descending limb, after the sharp bend of the loop. This part of the renal tubule is divided into a thin and thick ascending limb ; the thick portion is also known as the distal straight tubule , in contrast ...
The presence of aquaporin-1 channels in the thin segment facilitates high water permeability, crucial for water reabsorption as part of the kidney's countercurrent exchange mechanism. [ 4 ] [ 5 ] They can be distinguished from the vasa recta by the absence of blood, and they can be distinguished from the thick ascending limb by the thickness of ...
Each renal artery branches into segmental arteries, dividing further into interlobar arteries, which penetrate the renal capsule and extend through the renal columns between the renal pyramids. The interlobar arteries then supply blood to the arcuate arteries that run through the boundary of the cortex and the medulla.