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The myenteric plexus (or Auerbach's plexus) provides motor innervation to both layers of the muscular layer of the gut, having both parasympathetic and sympathetic input (although present ganglion cell bodies belong to parasympathetic innervation, fibers from sympathetic innervation also reach the plexus), whereas the submucous plexus provides secretomotor innervation to the mucosa nearest the ...
The nerve bundles of the submucosal plexus are finer than those of the myenteric plexus. Its function is to innervate cells in the epithelial layer and the smooth muscle of the muscularis mucosae. 14% of submucosal plexus neurons are sensory neurons – Dogiel type II, also known as enteric primary afferent neurons or intrinsic primary afferent ...
The muscle of the inner layer is arranged in circular rings around the tract, whereas the muscle of the outer layer is arranged longitudinally. The stomach has an extra layer, an inner oblique muscular layer. [1] Between the two muscle layers is the myenteric plexus (Auerbach's plexus). This controls peristalsis.
During normal prenatal development, cells from the neural crest migrate into the large intestine (colon) to form the networks of nerves called the myenteric plexus (Auerbach plexus) (between the smooth muscle layers of the gastrointestinal tract wall) and the submucosal plexus (Meissner plexus) (within the submucosa of the gastrointestinal ...
The myenteric plexus extends the full length of the gut, situated between the circular and longitudinal muscle layers. Beyond its primary motor and secretomotor functions, the myenteric plexus exhibits projections to submucosal ganglia and enteric ganglia in the pancreas and gallbladder, showcasing the interconnectivity within the ENS.
The plexus includes sensory receptors, such as chemoreceptors and mechanoreceptors, that are used to provide sensory input to the interneurons in the enteric nervous system. The plexus is the parasympathetic nucleus of origin for the vagus nerve and communicates with the medulla oblongata through both the anterior and posterior vagal nerves.
The myenteric plexus connects with the second plexus—the submucous plexus, or also known as Meissner’s plexus, which is buried in the submucosa and is responsible for helping to control blood flow and epithelial cell absorption and secretion. These groups of nerves are clearly super important for normal bowel function.
ICC-MY are present around the myenteric plexus and thought to be pacemaker cells for slow waves in the smooth muscle cells. Calcium imaging studies in the colon have shown that ICC-MY is innervated by nitrergic and cholinergic nerve terminals, though the nature of the contacts has not been well defined.