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The sense of smell should be tested individually in each nostril. [18] Many cases of congenital anosmia remain unreported and undiagnosed. Since the disorder is present from birth the individual may have little or no understanding of the sense of smell, hence is unaware of the deficit. [56] It may also lead to reduction of appetite. [57]
Instead, the diagnosis is made through a combination of clinical evaluations, smell tests, imaging studies, and the exclusion of other potential causes of smell loss. [1] [12] This comprehensive approach ensures that other conditions that might interfere with the sense of smell are ruled out before confirming a diagnosis of congenital anosmia. [13]
The underlying cause is due to the defective migration of GNRH neurons from olfactory placode to hypothalamus, leading to congenital GNRH deficiency. This leads to olfactory problems such as anosmia, optic defects like color blindness, and results in hypothalmic deficiencies associated with low levels of LH, affecting sex hormone testosterone in males or estrogen and progesterone in females.
People can be born with no sense of smell, ... If there is an odor from a noxious fume, “the neurons in the nose tell the brain that there is something dangerous to avoid,” tenOever said ...
Whiffing nasty things is a part of life—but a foul nose shouldn’t be. ENT doctors explain the reasons for a bad smell in your nose and how to get rid of it. 12 Reasons That Bad Smell in Your ...
This includes both total smell loss and dysosmia, or a distorted sense of smell. For example, a cup of coffee now smells like sewage. Both can take a huge toll.
Anosmia is the inability to perceive odor, or in other words a lack of functioning olfaction.Many patients may experience unilateral or bilateral anosmia. A temporary loss of smell can be caused by a blocked nose or infection. In contrast, a permanent loss of smell may be caused by death of olfactory receptor neurons in the nose or by brain injury in which there is damage to the
Injuries such as osseous fractures, skin burns, bruises and more serious ailments such as internal bleeding and appendicitis have a higher occurrence rate among people with the condition, since they don't have a concept of pain, they don't have a way of knowing if they have been injured or if they are suffering from pain in an area of their body that isn't the head or the stomach.