Search results
Results from the WOW.Com Content Network
Pharmacokinetics of 100 mg/day spironolactone and its metabolites Compound C max Tooltip Peak concentrations (day 1) C max Tooltip Peak concentrations (day 15) AUC Tooltip Area-under-the-curve concentrations (day 15) t 1/2 Tooltip Elimination half-life; Spironolactone: 72 ng/mL (173 nmol/L) 80 ng/mL (192 nmol/L) 231 ng•hour/mL (555 nmol ...
Download as PDF; Printable version ... and cyproterone acetate with more precise action and ... and breast side effects of spironolactone and to its drug ...
Spironolactone has been identified as an inhibitor of NRG1‐ERBB4 signaling. [142] Spironolactone has been found to act as a potent inhibitor of the pannexin 1 channel, and this action appears to be involved in its antihypertensive effects independently of MR antagonism. [143] Spironolactone has been found to block hERG channels. [144]
This template is within the scope of WikiProject Women's Health, a collaborative effort to improve the coverage of Women's Health on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.
To change this template's initial visibility, the |state= parameter may be used: {{Spironolactone | state = collapsed}} will show the template collapsed, i.e. hidden apart from its title bar. {{Spironolactone | state = expanded}} will show the template expanded, i.e. fully visible.
Spironolactone is a prodrug with a short terminal half-life of 1.4 hours. [ 5 ] [ 6 ] [ 7 ] The active metabolites of spironolactone have extended terminal half-lives of 13.8 hours for 7α-TMS, 15.0 hours for 6β-OH-7α-TMS, and 16.5 hours for canrenone, and accordingly, these metabolites are responsible for the therapeutic effects of the drug.
Download QR code; Print/export ... Download as PDF; Printable version; In other projects Wikimedia Commons; ... Template:Side effects of spironolactone in women in ...
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Donate