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Specialty: Hematology and oncology: Symptoms: Bleeding, bruising, fatigue, fever, increased risk of infections [2] Usual onset: All ages, [3] most common in 60s and 70s. [4] It is the most common malignant cancer in children, but the cure rates are also higher for them.
In epidemiology, a risk factor or determinant is a variable associated with an increased risk of disease or infection. [ 1 ] : 38 Due to a lack of harmonization across disciplines, determinant , in its more widely accepted scientific meaning , is often used as a synonym.
[1] [5] Other factors believed to increase risk include obesity, prolonged sitting, [8] [dubious – discuss] a chronic cough, and pelvic floor dysfunction. [2] Squatting while defecating may also increase the risk of severe hemorrhoids. [19] Evidence for these associations, however, is poor. [2]
The 6 pillars of lifestyle medicine.. Diet and lifestyle are major factors thought to influence susceptibility to many diseases. Substance use disorders, such as tobacco smoking, and excessive consumption of alcohol, and a lack of or too much exercise may also increase the risk of developing certain diseases, especially later in life.
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. [1] An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection.
Risk factors such as a person's background; lifestyle and environment are known to increase the likelihood of certain non-communicable diseases. They include age, gender, genetics, exposure to air pollution, and behaviors such as smoking, unhealthy diet and physical inactivity which can lead to hypertension and obesity, in turn leading to increased risk of many NCDs.
Being female is the single greatest risk factor for developing autoimmune disease than any other genetic or environmental risk factor yet discovered. [ 23 ] [ 24 ] Autoimmune conditions overrepresented in women include: lupus , primary biliary cholangitis , Graves' disease , Hashimoto's thyroiditis , and multiple sclerosis , among many others.
Obesity increases a person's risk of developing various metabolic diseases, cardiovascular disease, osteoarthritis, Alzheimer disease, depression, and certain types of cancer. [36] Depending on the degree of obesity and the presence of comorbid disorders, obesity is associated with an estimated 2–20 year shorter life expectancy.