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The table shown on the right can be used in a two-sample t-test to estimate the sample sizes of an experimental group and a control group that are of equal size, that is, the total number of individuals in the trial is twice that of the number given, and the desired significance level is 0.05. [4]
Lehr's [3] [4] (rough) rule of thumb says that the sample size (for each group) for the common case of a two-sided two-sample t-test with power 80% (=) and significance level = should be: , where is an estimate of the population variance and = the to-be-detected difference in the mean values of both samples.
Matched or independent study designs may be used. Power, sample size, and the detectable alternative hypothesis are interrelated. The user specifies any two of these three quantities and the program derives the third. A description of each calculation, written in English, is generated and may be copied into the user's documents.
When power calculations have to be performed, and a small pilot sample is available. Most power and sample size calculations are heavily dependent on the standard deviation of the statistic of interest. If the estimate used is incorrect, the required sample size will also be wrong.
The precision of an estimate is formally defined as 1/variance, and like power, increases (improves) with increasing sample size. Like power , a high level of precision is expensive; research grant applications would ideally include precision/cost analyses.
In statistics, an effect size is a value measuring the strength of the relationship between two variables in a population, or a sample-based estimate of that quantity. It can refer to the value of a statistic calculated from a sample of data, the value of one parameter for a hypothetical population, or to the equation that operationalizes how statistics or parameters lead to the effect size ...
For comparing significance tests, a meaningful measure of efficiency can be defined based on the sample size required for the test to achieve a given task power. [14] Pitman efficiency [15] and Bahadur efficiency (or Hodges–Lehmann efficiency) [16] [17] [18] relate to the comparison of the performance of statistical hypothesis testing procedures.
If the sample size is 1,000, then the effective sample size will be 500. It means that the variance of the weighted mean based on 1,000 samples will be the same as that of a simple mean based on 500 samples obtained using a simple random sample.