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Zafirlukast is FDA-approved for the prevention and treatment of asthma in adults and children older than 5 years old. [1] Like other leukotriene receptor antagonists, zafirlukast is thought to be useful for the long-term treatment of asthma, but it is generally less effective than inhaled glucocorticoids as monotherapy (which are the standard of care) or long-acting beta-2 agonists in ...
These 5 levels are indicators of what drug treatments should be administered. The guideline is as follows: [2] Step 1-2: Symptoms less than 4–5 days a week. Low-dose inhaled corticosteroids and formoterol combination therapy when required; Step 3: Symptoms most days, or waking with asthma once a week or more
Contraindications - lists situations in which the medication should not be used, for example in patients with other medical conditions such as kidney problems or allergies; Warnings - covers possible serious side effects that may occur (e.g., boxed warning)
The precursor to the English Pronouncing Dictionary was A Phonetic Dictionary of the English Language by Hermann Michaelis and Daniel Jones, [3] [4] published in Germany in 1913. In this work, the headwords of the dictionary were listed in phonemic transcription, followed by their spelling form, so the user needed to be aware of the phonemic ...
Pronunciation can change over time. Dictionaries may list the most commonly used forms of words, but as language changes, dictionaries change as well. At best, any guide to suggested pronunciation can reflect the preponderance of usage.
Speakers of non-rhotic accents, as in much of Australia, England, New Zealand, and Wales, will pronounce the second syllable [fəd], those with the father–bother merger, as in much of the US and Canada, will pronounce the first syllable [ˈɑːks], and those with the cot–caught merger but without the father–bother merger, as in Scotland ...
For example, you may pronounce cot and caught, do and dew, or marry and merry the same. This often happens because of dialect variation (see our articles English phonology and International Phonetic Alphabet chart for English dialects). If this is the case, you will pronounce those symbols the same for other words as well. [1]
On the other hand, "non-phonemic" [1] or "newspaper" [2] systems, commonly used in newspapers and other non-technical writings, avoid diacritics and literally "respell" words making use of well-known English words and spelling conventions, even though the resulting system may not have a one-to-one mapping between symbols and sounds.