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In the design of experiments in statistics, the lady tasting tea is a randomized experiment devised by Ronald Fisher and reported in his book The Design of Experiments (1935). [1] The experiment is the original exposition of Fisher's notion of a null hypothesis , which is "never proved or established, but is possibly disproved, in the course of ...
P-Values: The p-value is a measure of the probability that the observed data would occur by chance if the null hypothesis were true. In replication studies p-values help us determine whether the findings can be consistently replicated. A low p-value in a replication study indicates that the results are not likely due to random chance. [6]
The Design of Experiments is a 1935 book by the English statistician Ronald Fisher about the design of experiments and is considered a foundational work in experimental design. [ 2 ] [ 3 ] [ 4 ] Among other contributions, the book introduced the concept of the null hypothesis in the context of the lady tasting tea experiment. [ 5 ]
In more detail: the scientific method involves making conjectures (hypothetical explanations), predicting the logical consequences of hypothesis, then carrying out experiments or empirical observations based on those predictions. [4] A hypothesis is a conjecture based on knowledge obtained while seeking answers to the question.
The ZetaGrid project was set up to search for a counterexample to the Riemann hypothesis. Tomás Oliveira e Silva [7] searched for a counterexample to the Collatz conjecture. Finding new examples of numbers or objects with particular properties The Great Internet Mersenne Prime Search is searching for new Mersenne primes.
A pilot study is used to formulate the design of the full-scale experiment which then can be adjusted. [1] [2] The pilot study is potentially a critical insight to clinical trial design, recruitment and sample size of participants, treatment testing, and statistical analysis to improve the power of testing the hypothesis of the study. [2]
Edward Jenner tests his hypothesis for the protective action of mild cowpox infection for smallpox, the first vaccine (1796). Gregor Mendel's experiments with the garden pea led him to surmise many of the fundamental laws of genetics (dominant vs recessive genes, the 1–2–1 ratio, see Mendelian inheritance) (1856–1863).
A thought experiment is a hypothetical situation in which a hypothesis, theory, [a] or principle is laid out for the purpose of thinking through its consequences. The concept is also referred to using the German-language term Gedankenexperiment within the work of the physicist Ernst Mach [ 2 ] and includes thoughts about what may have occurred ...
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