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The presence of multipolar spindles in cancer cells is one of many differences from normal cells which can be seen under a microscope.Cancer is defined by uncontrolled cell growth and malignant cells can undergo cell division with multipolar spindles because they can group multiple centrosomes into two spindles.
Mitosis divides the chromosomes in a cell nucleus. During mitosis chromosome segregation occurs routinely as a step in cell division (see mitosis diagram). As indicated in the mitosis diagram, mitosis is preceded by a round of DNA replication, so that each chromosome forms two copies called chromatids.
An aster is a cellular structure shaped like a star, consisting of a centrosome and its associated microtubules during the early stages of mitosis in an animal cell. [1]: 221 Asters do not form during mitosis in plants. Astral rays, composed of microtubules, radiate from the centrosphere and look like a cloud. Astral rays are one variant of ...
English: A diagram of mitosis stages Interphase (G₂): In this substage, the cell prepares for nuclear division and a protein that makes microtubles for cell division is synthesized. Prophase: The longest stage of mitosis. In this stage the chromosomes become visible and the centrioles separate and move to opposite poles of the cell.
This is an accepted version of this page This is the latest accepted revision, reviewed on 19 December 2024. Process in which chromosomes are replicated and separated into two new identical nuclei For the type of cell division in sexually reproducing organisms used to produce gametes, see Meiosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...
Micrograph showing condensed chromosomes in blue, kinetochores in pink, and microtubules in green during metaphase of mitosis. In cell biology, the spindle apparatus is the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter cells.
The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.
Diagram showing events that can lead to mitotic catastrophe and the potential outcomes. One usage of the term mitotic catastrophe is to describe an oncosuppressive mechanism (i.e. a mechanism to prevent the proliferation of cancerous cells and the development of tumors) that occurs when cells undergo and detect a defective mitosis has occurred. [5]
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