Search results
Results from the WOW.Com Content Network
There are many proposed causes of sarcopenia and it is likely the result of multiple interacting factors. Understanding of the causes of sarcopenia is incomplete, however, changes in hormones, immobility, age-related muscle changes, nutrition, and neurodegenerative changes have all been recognized as potential causative factors.
Frailty can have various symptoms including muscle weakness (reduced grip strength), slower walking speed, exhaustion, unintentional weight loss, and frequent falls. [ 3 ] [ 4 ] Older people with certain medical conditions such as diabetes , heart disease and dementia , are also more likely to have frailty.
Muscle atrophy is the loss of skeletal muscle mass. It can be caused by immobility, aging, malnutrition, medications, or a wide range of injuries or diseases that impact the musculoskeletal or nervous system. Muscle atrophy leads to muscle weakness and causes disability.
Weakness comes on slowly (over months to years) in an asymmetric manner and progresses steadily, leading to severe weakness and wasting of arm and leg muscles. IBM is more common in men than women. [10] Patients may become unable to perform activities of daily living and most require assistive devices within 5 to 10 years of symptom onset.
On electron microscopy, nemaline bodies within the affected muscle fibers may be found. These bodies are sometimes crisply rod-shaped, but can also be irregular and punctate. The rods may be found alongside atrophic muscle fibers, and may be seen arising from the thickened Z-discs of the sarcolemmae. Affected fibers may be vacuolated or ...
Dynapenia (pronounced dahy-nuh-pē-nē-a, Greek translation for poverty of strength, power, or force) is the loss of muscular strength not caused by neurological or muscular disease that typically is associated with older adults. [1] Dynapenia is the loss of muscle strength, rather than the loss of muscle mass . The preservation of muscular ...
Symptoms: Varying degrees muscle weakness, double vision, drooping eyelids, trouble talking, trouble walking [1] Usual onset: Women under 40, men over 60 [1] Duration: Long term [1] Causes: Autoimmune disease [1] Diagnostic method: Blood tests for specific antibodies, edrophonium test, nerve conduction studies [1] Differential diagnosis
overlapping symptoms (such as muscle weakness, pain, elevated CK); that delaying treatment for an inflammatory myopathy, in order to exclude potential non-inflammatory myopathies, may cause irreversible damage (although administering immunosuppressants and glucocorticosteroids to non-inflammatory myopathies may also cause damage);