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Elastic fibers stain well with aldehyde fuchsin, orcein, [16] and Weigert's elastic stain in histological sections. The permanganate-bisulfite-toluidine blue reaction is a highly selective and sensitive method for demonstrating elastic fibers under polarizing optics.
This delay between cell-cell contact and onset of proliferation inhibition is shortened as the culture becomes more confluent. Thus, it may be reasonably concluded that cell-cell contact is an essential condition for contact inhibition of proliferation, but is by itself insufficient for mitotic inhibition.
Direct contact between cells allows the receptors on one cell to bind the small molecules attached to the plasma membrane of different cell. In eukaryotes, many of the cells during early development communicate through direct contact. [5] Synaptic signaling, an integral part of nervous system activity, occurs between neurons and target cells.
Elastic fiber in the body is a mixture of amorphous elastin and fibrous fibrillin. Both components are primarily made of smaller amino acids such as glycine , valine , alanine , and proline . [ 11 ] [ 14 ] The total elastin ranges from 58 to 75% of the weight of the dry defatted artery in normal canine arteries. [ 15 ]
In molecular biology, fibrous proteins or scleroproteins are one of the three main classifications of protein structure (alongside globular and membrane proteins). [1] Fibrous proteins are made up of elongated or fibrous polypeptide chains which form filamentous and sheet-like structures.
In cord arrangement, bundles of collagen and matrix are distributed in regular alternate patterns. In sheath arrangement, collagen bundles and matrix are distributed in irregular patterns, sometimes in the form of a network. It is similar to areolar tissue, but in DRCT elastic fibers are completely absent. [2]
Link proteins such as vinculin, spectrin and actomyosin stabilize the proteoglycans and organize elastic fibers in the ECM. [2] Changes in the density of ground substance can allow collagen fibers to form aberrant cross-links. [2] Loose connective tissue is characterized by few fibers and cells, and a relatively large amount of ground substance.
Schematic of cell adhesion. Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix, a gel-like structure containing molecules released ...