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The efficacy of intravenous ascorbic acid therapy came under scrutiny of the medical and science community, following the numerous high-profile studies authored by Linus Pauling in the 1970s. [19] The experimental design of Pauling and Cameron's 1976 publication, "Supplemental ascorbate in the supportive treatment of cancer", [ 25 ] had ...
The Linus Pauling Institute is a research institute located at the Oregon State University with a focus on health maintenance. The mission statement of the institute is to determine the functional roles of micronutrients and phytochemicals in promoting optimal health and to treat or prevent human disease, and to determine the role of oxidative stress and inflammation in health and disease.
In the 1960s, Linus Pauling, after contact with Irwin Stone, [91] began actively promoting vitamin C as a means to greatly improve human health and resistance to disease. The Pauling's book How to Live Longer and Feel Better, [92] first published in 1986, [93] was a bestseller and advocated taking more than 10 grams per day orally, thus ...
The book characterizes the inability of humans and some other animals to produce vitamin C (ascorbic acid) in terms of evolution and Pauling's concept of "molecular disease" (first articulated in his 1949 study, "Sickle Cell Anemia, a Molecular Disease"). Pauling argues that the loss of vitamin C synthesis first arose as a molecular disease ...
The Linus Pauling Institute still exists, but moved in 1996 from Palo Alto, California, to Corvallis, Oregon, where it is part of the Linus Pauling Science Center at Oregon State University. [ 181 ] [ 182 ] [ 183 ] The Valley Library Special Collections at Oregon State University contain the Ava Helen and Linus Pauling Papers, including ...
While at Caltech, Itano joined the lab of Linus Pauling and began working on sickle cell anemia, a genetic disease that Pauling was interested in. [4] Pauling was convinced that sickle cell disease was caused by defective hemoglobin, and set Itano to find out what made sickle cell hemoglobin chemically different. [9]
In the late 1960s, Linus Pauling introduced the expression "orthomolecular" [11] to express the idea of the right molecules in the right amounts. [11] Since the first claims of medical breakthroughs with vitamin C by Pauling and others, findings on the health effects of vitamin C have been controversial and contradictory.
The higher the BP, the greater is the chance of heart attack, heart failure, stroke, and kidney disease. For individuals 40–70 years of age, each increment of 20 mm Hg in systolic BP (SBP) or 10 mm Hg in diastolic BP (DBP) doubles the risk of CVD across the entire BP range from 115/75 to 185/115 mm Hg.”.
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