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The most common signs and symptoms are bleeding, which can vary from minor to severe, rectal prolapse and incomplete evacuation (35%-76% of cases). [4] According to one report, constipation is present in about 55% of cases, but diarrhea is present in 20%–40% of cases. [1] Reported symptoms are: Hematochezia (lower gastrointestinal bleeding).
Solitary rectal ulcer syndrome (SRUS) is a rare benign disease characterized by symptoms, clinical findings, and histological abnormalities. [9] Only 40% of patients have ulcers; 20% of patients have a single ulcer, and the remaining lesions range in size and form from broad-based polypoid to hyperemic mucosa. [10]
Depending on the amount of the blood loss, symptoms may include shock. Upper gastrointestinal bleeding can be caused by peptic ulcers, gastric erosions, esophageal varices, and rarer causes such as gastric cancer. The initial assessment includes measurement of the blood pressure and heart rate, as well as blood tests to determine the hemoglobin.
PPI is the most popular agent in peptic ulcer prevention. [15] However, there is no evidence that H2 antagonists can prevent stomach bleeding for those taking NSAIDs. [15] Although misoprostol is effective in preventing peptic ulcer, its properties of promoting abortion and causing gastrointestinal distress limit its use. [15]
Symptoms traditionally linked to SIBO include bloating, diarrhea, constipation, and abdominal pain/discomfort. Steatorrhea may be seen in more severe cases. [4] Bacterial overgrowth can cause a variety of symptoms, many of which are also found in other conditions, making the diagnosis challenging at times. [4]
Oral symptoms can be similar to lesions occurring elsewhere in the digestive tract, with a pattern of swelling, inflammation, ulcers, and fissures. If these signs are present, then patients are more likely to also have anal and esophageal lesions and experience other extra-intestinal disease manifestations. [2]
Chronic constipation; Fecal incontinence – paradoxical overflow diarrhea as a result of liquid stool passing around the obstruction; Abdominal pain and bloating; Loss of appetite; Complications may include necrosis and ulcers of the rectal tissue, which if untreated can cause death. [citation needed]
Indigestion is a diagnosis related to a combination of symptoms that can be attributed to "organic" or "functional" causes. [13] Organic dyspepsia should have pathological findings upon endoscopy, like an ulcer in the stomach lining in peptic ulcer disease. [13]