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Fibroma of tendon sheath is a benign tumor that presents as a small subcutaneous nodule that slowly increases in size. [1] This is a notably uncommon condition. According to case report literature, the tumors often have a multinodular growth pattern, with individual nodules being composed of bland, slender, spindle-shaped cells (myofibroblasts) in a dense, fibrous matrix.” [2] A common ...
In Dupuytren's contracture, the palmar fascia within the hand becomes abnormally thick, which can cause the fingers to curl and can impair finger function. The main function of the palmar fascia is to increase grip strength; thus, over time, Dupuytren's contracture decreases a person's ability to hold objects and use the hand in many different ...
A ganglion cyst is a fluid-filled bump associated with a joint or tendon sheath. [3] It most often occurs at the back of the wrist, followed by the front of the wrist. [3] [4] The cause is unknown. [3] The underlying mechanism is believed to involve an outpouching of the synovial membrane. [4] Diagnosis is typically based on examination.
Xanthoma tendinosum (also tendon xanthoma or tendinous xanthoma [5]) is clinically characterized by papules and nodules found in the tendons of the hands, feet, and heel. [ 2 ] : 531 Also associated with familial hypercholesterolemia (FH).
Histopathology of localized TGCT arising in hand finger. H&E stain. Localized TGCT is sometimes referred to as localized pigmented villonodular synovitis (L-PVNS), giant cell tumor of the tendon sheath (GCT-TS), nodular tenosynovitis, localized nodular tenosynovitis, and L-TGCT. [2]: 1 [3]: 100 The localized form of TGCT is more common.
Aponeurotic fibroma, also known as calcifying aponeurotic fibroma, and juvenile aponeurotic fibroma is characterized by a lesion that usually presents as a painless, solitary, deep fibrous nodule, often adherent to tendon, fascia, or periosteum, on the hands and feet. [1]
Nodules in skin include dermatofibroma [5] and pyogenic granuloma. [6] Nodules may form on tendons and muscles in response to injury, [7] and are frequently found on vocal cords. [8] They may occur in organs such as the lung, [9] or thyroid, [10] or be a sign in other medical conditions such as rheumatoid arthritis. [11]
About 20% of people with rheumatoid arthritis develop rheumatoid nodules, which are linked to more severe erosive disease in those patients. [2] The nodules are more common in men, typically manifest in the fifth decade of life, and are primarily found on extensor surfaces like the backs of the fingers and elbows, though they can occur anywhere.