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Side effects of statins include muscle pain, ... atorvastatin showed greater cholesterol-lowering effect in women than in men compared to rosuvastatin. [49]
When examining the cost-effectiveness of statin use in older adults, the researchers report that statins were cost-effective, with the cost per quality-adjusted life years gained below £3,502 ...
Research published in Circulation: Cardiovascular Quality and Outcomes found 25 percent more cases of newly diagnosed type 2 diabetes in the statin group compared to those not taking a statin. The ...
A new way of determining heart disease risk may result in millions fewer people getting prescriptions for statins, according to new research. ... the researchers compared estimates from the new ...
The inhibitory activity of cerivastatin was compared to that of other statins, specifically lovastatin, simvastatin and pravastatin. This comparison was made by determining the IC50 values of each compound. These values were 77 nM, 66 nM and 176 nM for these statins, respectively, while the value for cerivastatin was found to be 1.1 nM.
In four RCTs a mean rosuvastatin dose of 16 mg/day reduced LDL cholesterol by 48.8% and reduced myocardial infarction, relative risk, 0.82 (95% CI 0.73 to 0.93) as compared to placebo. Thus despite reducing LDL cholesterol by a much lesser amount with fluvastatin than atorvastatin and rosuvastatin, fluvastatin reduced myocardial infarction ...
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