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Unilateral adrenal hemorrhage is the condition when bleeding occurs in ... leaving a hypointense rim on T1- and T2-weighted images due to the hemosiderin deposition ...
T2*-weighted imaging of the brain 26 weeks after subarachnoid hemorrhage, showing hemosiderin deposits as hypointense areas. [1] T 2 *-weighted imaging is an MRI sequence to quantify observable or effective T 2 (T2* or "T2-star"). In this sequence, hemorrhages and hemosiderin deposits become hypointense. [2]
Gradient recalled echo (GRE) imaging is the conventional way to detect hemorrhage in CAA, however SWI is a much more sensitive technique that can reveal many micro-hemorrhages that are missed on GRE images. [7] A conventional gradient echo T2*-weighted image (left, TE=20 ms) shows some low-signal foci associated with CAA.
T1-weighted T2-weighted High: Fat [33] [34] Subacute hemorrhage [34] Melanin [34] Protein-rich fluid [34] Slowly flowing blood [34] Paramagnetic substances, such as gadolinium, manganese, copper [34] Cortical pseudolaminar necrosis [34] More water content, [33] as in edema, tumor, infarction, inflammation and infection [34]
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Lower signal for more water content, [1] as in edema, tumor, infarction, inflammation, infection, hyperacute or chronic hemorrhage. [2] High signal for fat [1] [2] High signal for paramagnetic substances, such as MRI contrast agents [2] Standard foundation and comparison for other sequences T2 weighted: T2
Adrenal hemorrhage characteristic of the Waterhouse–Friderichsen syndrome has been identified in several autopsies of patients who died of sepsis secondary to capnocytophaga canimorsus infection. [8] Viruses may also be implicated in adrenal problems: Cytomegalovirus can cause adrenal insufficiency, [9] especially in the immunocompromised.
Adrenocortical carcinoma (ACC) is an aggressive cancer originating in the cortex (steroid hormone-producing tissue) of the adrenal gland.. Adrenocortical carcinoma is remarkable for the many hormonal syndromes that can occur in patients with steroid hormone-producing ("functional") tumors, including Cushing's syndrome, Conn syndrome, virilization, and feminization.