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Prior to this it was known as Churg–Strauss syndrome, named after Jacob Churg and Lotte Strauss, who first published about the syndrome in 1951 using the term allergic granulomatosis to describe it. [3] It is a type of systemic necrotizing vasculitis. Effective treatment of EGPA requires suppression of the immune system with medication.
Lotte Strauss (15 April 1913 – 4 July 1985) was a German-American pathologist. [1] [2] She was born in Nuremberg, Germany. [1] Strauss, alongside Jacob Churg, attributed her name to Churg–Strauss syndrome, which is now known as eosinophilic granulomatosis with polyangiitis. [3] She was one of the founders of the Society for Pediatric ...
The revised five-factor score is associated with five-year mortality from GPA and is based on these criteria: Age greater than 65 years, cardiac symptoms, gastrointestinal involvement, chronic kidney disease, and the absence of ear, nose, and throat symptoms. [7] With corticosteroids and cyclophosphamide, five-year survival is over 80%. [13]
Churg-Strauss syndrome is also called eosinophilic granulomatosis with polyangiitis, or EGPA. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 ...
Leukotriene receptor antagonist-associated Churg–Strauss syndrome may occur in asthma patients being treated with leukotriene receptor antagonists, occurring 2 days to 10 months after the antagonist has been started, with features of the syndrome including peripheral eosinophilia, pulmonary infiltrates, and less commonly neuropathy, sinusitis, and cardiomyopathy.
Legius syndrome; Leiner's disease; Lelis syndrome; Lemierre's syndrome; Lennox–Gastaut syndrome; Lenz microphthalmia syndrome; Lenz–Majewski syndrome; Leriche's syndrome; Leschke syndrome; Lesch–Nyhan syndrome; Lethal congenital contracture syndrome; Lethal white syndrome; Leukotriene receptor antagonist-associated Churg–Strauss ...
Jacob Churg [needs IPA] (16 July 1910, Daŭhinava, Russian Empire – 27 July 2005, New York City) was a Polish-American pathologist. Churg, together with Lotte Strauss , has given his name to Churg–Strauss syndrome, now known as eosinophilic granulomatosis with polyangiitis .
Mepolizumab has been investigated or is under investigation for the treatment of atopic dermatitis, hypereosinophilic syndrome (HES), eosinophilic esophagitis (EoE), [16] nasal polyposis, eosinophilic granulomatosis with polyangiitis, and chronic obstructive pulmonary disease. [citation needed]