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PCBs collect in body fat and milk fat. [56] PCBs biomagnify up the food web and are present in fish and overflow of contaminated aquifers. [57] Human infants are exposed to PCBs through breast milk or by intrauterine exposure through transplacental transfer of PCBs [56] and are at the top of the food chain. [58]: 249ff
Ortho-PCBs may alter hormone regulation through disruption of the thyroid hormone transport by binding to transthyretin. [8] Coplanar PCBs are similar to dioxins and furans, both bind to the aryl hydrocarbon receptor (AhR) in organisms and may exert dioxin-like effects, in addition to the effects shared with non-coplanar PCBs.
Polychlorinated biphenyls (PCBs), derived from biphenyl, of which 12 are "dioxin-like". Under certain conditions PCBs may form dibenzofurans through partial oxidation. Polybrominated analogs of the above classes may have similar effects. "Dioxin" can also refer to 1,4-dioxin or p-dioxin, the basic chemical unit of the more complex dioxins. This ...
Woodruff, who has studied the effect of some chemicals found in plastics on human health, reproduction, and development for two decades, first started looking into microplastics in 2021.
The oral LD50 for guinea pigs is as low as 0.5 to 2 μg/kg body weight, whereas the oral LD50 for hamsters can be as high as 1 to 5 mg/kg body weight, a difference of as much as thousandfold or more, and even among rat strains there may be thousandfold differences.
PCBs are toxic to fish at high doses, and associated with spawning failure at low doses. Human exposure occurs through food, and is associated with reproductive failure and immune suppression. Immediate effects of PCB exposure include pigmentation of nails and mucous membranes and swelling of the eyelids, along with fatigue, nausea, and vomiting.
(Reuters) -A Washington jury on Tuesday ordered Bayer to pay $100 million to four people who say they were sickened by toxic chemicals known as PCBs at a Seattle-area school, but found the company ...
Nov. 13, 2023: An additional lab, SGS Galson, received samples of the air in Poe Hall. The company reported the results to NC State on Nov. 14. The results did not appear to indicate ...
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