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Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. [10] It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent (dual antiplatelet therapy). [10] It is taken by mouth. [10]
An antiplatelet drug (antiaggregant), also known as a platelet agglutination inhibitor or platelet aggregation inhibitor, is a member of a class of pharmaceuticals that decrease platelet aggregation [1] and inhibit thrombus formation.
Metabolism of ticlopidine, clopidogrel and prasugrel to an active metabolite. Clopidogrel is a prodrug that is metabolized by two pathways. In one of the pathway most of the dose of clopidogrel (85%) is hydrolyzed by esterases to an inactive carboxylic acid derivate and rapidly cleared via glucoridination followed by renal excretion.
In nursing education, a clerkship refers to the clinical courses conducted by students during their final year of studies. The student satisfaction with the clerkship is a determinant factor in selection of nursing field. [9] [10] Physician assistant programs in the United States used the term in the same manner. [11] [12] [13]
[55] [57] An interaction between PPIs and the metabolism of the platelet inhibitor clopidogrel is known and this drug is also often used in people with cardiac disease. [58] [59] [22] There are associations with an increased risk of stroke, but this appears to be more likely to occur in people who already have an elevated risk. [60]
Nursing A nurse checks a patient's blood pressure. Occupation Activity sectors Nursing Description Competencies Caring for general and specialized well-being of patients Education required Qualifications in terms of statutory regulations according to national, state, or provincial legislation in each country Fields of employment Hospital Clinic Laboratory Research Education Home care Related ...
The nurse manager is the nurse with management responsibilities of a nursing unit. They typically report to a service director. They have primary responsibilities for staffing, budgeting, and day-to-day operations of the unit, bed site teaching, complaint investigations & conducting educational programs at unit base.
The accepted management of unstable angina and acute coronary syndrome is therefore empirical treatment with aspirin, a second platelet inhibitor such as clopidogrel, prasugrel or ticagrelor, and heparin (usually a low-molecular weight heparin), with intravenous nitroglycerin and opioids if the pain persists.