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Promethazine is preferred during pregnancy because it is an older drug and there is more data regarding the use of it during pregnancy. Second-choice medications, which are used if Promethazine isn't tolerated or the patient cannot take it, are metoclopramide or prochlorperazine. [15] [13]
When taken in prescribed quantities, codeine-promethazine is quite safe, [16] but dangers arise in higher doses since promethazine is a depressant of the central nervous system (CNS), and codeine is a respiratory depressant. When codeine is taken in very large amounts, it can cause one to stop breathing. [16]
Codeine is also available in conjunction with the anti-nausea medication promethazine in the form of a syrup. Brand named as Phenergan with Codeine or in generic form as promethazine with Codeine, it began to be mixed with soft drinks in the 1990s as a recreational drug, called 'syrup', 'lean', or ' purple drank '. [ 63 ]
In 1947, it synthesized promethazine, a phenothiazine derivative, which was found to have more pronounced sedative and antihistaminic effects than earlier drugs. [ 59 ] : 77 A year later, the French surgeon Pierre Huguenard used promethazine together with pethidine as part of a cocktail to induce relaxation and indifference in surgical patients.
Taking expired vitamins is generally considered safe—but there’s a catch. “Usually, expired vitamins won’t harm you, but likely will lose potency. “Usually, expired vitamins won’t harm ...
Cold medicines are a group of medications taken individually or in combination as a treatment for the symptoms of the common cold and similar conditions of the upper respiratory tract.
Diphenhydramine (Benadryl) was synthesized in 1943, tripelennamine (Pyribenzamine) was patented in 1946, and promethazine (Phenergan) was synthesized in 1947 and launched in 1949. [22] [23] [24] By 1950, at least 20 antihistamines had been marketed. [25]
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related to: when to take phenerganThe lowest prices on specific drugs - Family Circle