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  2. Ramelteon - Wikipedia

    en.wikipedia.org/wiki/Ramelteon

    Ramelteon is an analogue of melatonin and is a selective agonist of the melatonin MT 1 and MT 2 receptors. [3] The half-life and duration of ramelteon are much longer than those of melatonin. [7] Ramelteon is not a benzodiazepine or Z-drug and does not interact with GABA receptors, instead having a distinct mechanism of action. [3] [8]

  3. Somnifacient - Wikipedia

    en.wikipedia.org/wiki/Somnifacient

    Etizolam is a benzodiazepine somnifacient for treating insomnia. Somnifacient (from Latin somnus, sleep [1]), also known as sedatives or sleeping pills, is a class of medications that induces sleep.

  4. Melatonin receptor agonist - Wikipedia

    en.wikipedia.org/wiki/Melatonin_receptor_agonist

    In 2005 ramelteon (Rozerem) was approved in the US indicated for treatment of insomnia, characterized as difficulty with falling asleep, in adults. [ citation needed ] Melatonin in the form of prolonged release (trade name Circadin ) was approved in 2007 in Europe (EU) for use as a short-term treatment, in patients 55 years or older, for ...

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  6. TIK-301 - Wikipedia

    en.wikipedia.org/wiki/TIK-301

    TIK-301 is a high affinity nonselective MT 1 /MT 2 agonist. [8] Studies show that it is more potent and more effective than melatonin.Its affinity for MT 1 is similar to that of melatonin (pK i =10.38, K i =81pM) and its affinity for MT 2 is slightly higher (pK i =10.38, K i = 42pM).

  7. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

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    This article was reviewed by Kelly Brown MD, MBA. If you’ve just started taking Cialis, don’t be alarmed if you feel a little off. Like other medications for the treatment of (ED), Cialis ...

  8. Tasimelteon - Wikipedia

    en.wikipedia.org/wiki/Tasimelteon

    Tasimelteon, sold under the brand name Hetlioz, is a medication approved by the U.S. Food and Drug Administration (FDA) [3] in January 2014, for the treatment of non-24-hour sleep–wake disorder (also called non-24, N24 and N24HSWD). [4]

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